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Small-angle X-ray and neutron scattering
Small-angle scattering (SAS) is a technique that is able to probe the structural organization
of matter and quantify its response to changes in external conditions. X-ray and neutron …
of matter and quantify its response to changes in external conditions. X-ray and neutron …
Evolving SAXS versatility: solution X-ray scattering for macromolecular architecture, functional landscapes, and integrative structural biology
CA Brosey, JA Tainer - Current opinion in structural biology, 2019 - Elsevier
Highlights•SAXS captures architecture and dynamics to elucidate molecular
ensembles.•SAXS advances now probe key thermodynamic and kinetic properties of …
ensembles.•SAXS advances now probe key thermodynamic and kinetic properties of …
[HTML][HTML] ATSAS 3.0: expanded functionality and new tools for small-angle scattering data analysis
K Manalastas-Cantos, PV Konarev… - Applied …, 2021 - journals.iucr.org
The ATSAS software suite encompasses a number of programs for the processing,
visualization, analysis and modelling of small-angle scattering data, with a focus on the data …
visualization, analysis and modelling of small-angle scattering data, with a focus on the data …
pH-dependent structural transitions in cationic ionizable lipid mesophases are critical for lipid nanoparticle function
Lipid nanoparticles (LNPs) are advanced core-shell particles for messenger RNA (mRNA)
based therapies that are made of polyethylene glycol (PEG) lipid …
based therapies that are made of polyethylene glycol (PEG) lipid …
[HTML][HTML] ATSAS 2.8: a comprehensive data analysis suite for small-angle scattering from macromolecular solutions
ATSAS is a comprehensive software suite for the analysis of small-angle scattering data
from dilute solutions of biological macromolecules or nanoparticles. It contains applications …
from dilute solutions of biological macromolecules or nanoparticles. It contains applications …
BioXTAS RAW: improvements to a free open-source program for small-angle X-ray scattering data reduction and analysis
BioXTAS RAW is a graphical-user-interface-based free open-source Python program for
reduction and analysis of small-angle X-ray solution scattering (SAXS) data. The software is …
reduction and analysis of small-angle X-ray solution scattering (SAXS) data. The software is …
Polysarcosine-functionalized lipid nanoparticles for therapeutic mRNA delivery
SS Nogueira, A Schlegel, K Maxeiner… - ACS Applied Nano …, 2020 - ACS Publications
Polysarcosine (pSar) is a polypeptoid based on the endogenous amino acid sarcosine (N-
methylated glycine), which has previously shown potent stealth properties. Here, lipid …
methylated glycine), which has previously shown potent stealth properties. Here, lipid …
Short prokaryotic Argonautes provide defence against incoming mobile genetic elements through NAD+ depletion
M Zaremba, D Dakineviciene, E Golovinas… - Nature …, 2022 - nature.com
Argonaute (Ago) proteins are found in all three domains of life. The so-called long Agos are
composed of four major domains (N, PAZ, MID and PIWI) and contribute to RNA silencing in …
composed of four major domains (N, PAZ, MID and PIWI) and contribute to RNA silencing in …
Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2
The coronavirus SARS-CoV-2 is the cause of the ongoing COVID-19 pandemic. Therapeutic
neutralizing antibodies constitute a key short-to-medium term approach to tackle COVID-19 …
neutralizing antibodies constitute a key short-to-medium term approach to tackle COVID-19 …
Conformational buffering underlies functional selection in intrinsically disordered protein regions
Many disordered proteins conserve essential functions in the face of extensive sequence
variation, making it challenging to identify the mechanisms responsible for functional …
variation, making it challenging to identify the mechanisms responsible for functional …