Small-angle X-ray and neutron scattering

CM Jeffries, J Ilavsky, A Martel, S Hinrichs… - Nature Reviews …, 2021 - nature.com
Small-angle scattering (SAS) is a technique that is able to probe the structural organization
of matter and quantify its response to changes in external conditions. X-ray and neutron …

Evolving SAXS versatility: solution X-ray scattering for macromolecular architecture, functional landscapes, and integrative structural biology

CA Brosey, JA Tainer - Current opinion in structural biology, 2019 - Elsevier
Highlights•SAXS captures architecture and dynamics to elucidate molecular
ensembles.•SAXS advances now probe key thermodynamic and kinetic properties of …

[HTML][HTML] ATSAS 2.8: a comprehensive data analysis suite for small-angle scattering from macromolecular solutions

D Franke, MV Petoukhov, PV Konarev… - Journal of applied …, 2017 - scripts.iucr.org
ATSAS is a comprehensive software suite for the analysis of small-angle scattering data
from dilute solutions of biological macromolecules or nanoparticles. It contains applications …

[PDF][PDF] ATSAS 3.0: expanded functionality and new tools for small-angle scattering data analysis

K Manalastas-Cantos, PV Konarev… - Journal of applied …, 2021 - journals.iucr.org
The ATSAS software suite encompasses a number of programs for the processing,
visualization, analysis and modelling of small-angle scattering data, with a focus on the data …

[PDF][PDF] BioXTAS RAW: improvements to a free open-source program for small-angle X-ray scattering data reduction and analysis

JB Hopkins, RE Gillilan, S Skou - Journal of applied crystallography, 2017 - journals.iucr.org
BioXTAS RAW is a graphical-user-interface-based free open-source Python program for
reduction and analysis of small-angle X-ray solution scattering (SAXS) data. The software is …

Polysarcosine-functionalized lipid nanoparticles for therapeutic mRNA delivery

SS Nogueira, A Schlegel, K Maxeiner… - ACS Applied Nano …, 2020 - ACS Publications
Polysarcosine (pSar) is a polypeptoid based on the endogenous amino acid sarcosine (N-
methylated glycine), which has previously shown potent stealth properties. Here, lipid …

Short prokaryotic Argonautes provide defence against incoming mobile genetic elements through NAD+ depletion

M Zaremba, D Dakineviciene, E Golovinas… - Nature …, 2022 - nature.com
Argonaute (Ago) proteins are found in all three domains of life. The so-called long Agos are
composed of four major domains (N, PAZ, MID and PIWI) and contribute to RNA silencing in …

Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2

TF Custódio, H Das, DJ Sheward, L Hanke… - Nature …, 2020 - nature.com
The coronavirus SARS-CoV-2 is the cause of the ongoing COVID-19 pandemic. Therapeutic
neutralizing antibodies constitute a key short-to-medium term approach to tackle COVID-19 …

pH-dependent structural transitions in cationic ionizable lipid mesophases are critical for lipid nanoparticle function

J Philipp, A Dabkowska, A Reiser… - Proceedings of the …, 2023 - National Acad Sciences
Lipid nanoparticles (LNPs) are advanced core-shell particles for messenger RNA (mRNA)
based therapies that are made of polyethylene glycol (PEG) lipid …

[PDF][PDF] 2017 publication guidelines for structural modelling of small-angle scattering data from biomolecules in solution: an update

J Trewhella, AP Duff, D Durand, F Gabel… - … Section D: Structural …, 2017 - journals.iucr.org
In 2012, preliminary guidelines were published addressing sample quality, data acquisition
and reduction, presentation of scattering data and validation, and modelling for biomolecular …