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Advances in COVID-19 mRNA vaccine development
E Fang, X Liu, M Li, Z Zhang, L Song, B Zhu… - Signal transduction and …, 2022 - nature.com
To date, the coronavirus disease 2019 (COVID-19) caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has determined 399,600,607 cases and 5,757,562 …
syndrome coronavirus 2 (SARS-CoV-2) has determined 399,600,607 cases and 5,757,562 …
Emerging COVID-19 variants and their impact on SARS-CoV-2 diagnosis, therapeutics and vaccines
The emergence of novel and evolving variants of SARS-CoV-2 has fostered the need for
change in the form of newer and more adaptive diagnostic methods for the detection of …
change in the form of newer and more adaptive diagnostic methods for the detection of …
The efficacy and effectiveness of the COVID-19 vaccines in reducing infection, severity, hospitalization, and mortality: a systematic review
I Mohammed, A Nauman, P Paul… - Human vaccines & …, 2022 - Taylor & Francis
With the relatively rapid development of the COVID-19 pandemic, vaccine development has
become crucial for limiting disease transmission. The accelerated growth in the approved …
become crucial for limiting disease transmission. The accelerated growth in the approved …
Immunological mechanisms of vaccine-induced protection against COVID-19 in humans
Most COVID-19 vaccines are designed to elicit immune responses, ideally neutralizing
antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including …
antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including …
Effect of 2 inactivated SARS-CoV-2 vaccines on symptomatic COVID-19 infection in adults: a randomized clinical trial
N Al Kaabi, Y Zhang, S **a, Y Yang, MM Al Qahtani… - Jama, 2021 - jamanetwork.com
Importance Although effective vaccines against COVID-19 have been developed, additional
vaccines are still needed. Objective To evaluate the efficacy and adverse events of 2 …
vaccines are still needed. Objective To evaluate the efficacy and adverse events of 2 …
SARS-CoV-2 vaccines strategies: a comprehensive review of phase 3 candidates
The new SARS-CoV-2 virus is an RNA virus that belongs to the Coronaviridae family and
causes COVID-19 disease. The newly sequenced virus appears to originate in China and …
causes COVID-19 disease. The newly sequenced virus appears to originate in China and …
COVID-19 vaccines: where we stand and challenges ahead
G Forni, A Mantovani - Cell Death & Differentiation, 2021 - nature.com
In the eleven months elapsed since the identification of the SARS-CoV-2 virus and its
genome, an exceptional effort by the scientific community has led to the development of over …
genome, an exceptional effort by the scientific community has led to the development of over …
Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised …
Background Older adults (aged≥ 70 years) are at increased risk of severe disease and
death if they develop COVID-19 and are therefore a priority for immunisation should an …
death if they develop COVID-19 and are therefore a priority for immunisation should an …
[HTML][HTML] Safety, tolerability, and immunogenicity of an inactivated SARS-CoV-2 vaccine in healthy adults aged 18–59 years: a randomised, double-blind, placebo …
Y Zhang, G Zeng, H Pan, C Li, Y Hu, K Chu… - The Lancet infectious …, 2021 - thelancet.com
Background With the unprecedented morbidity and mortality associated with the COVID-19
pandemic, a vaccine against COVID-19 is urgently needed. We investigated CoronaVac …
pandemic, a vaccine against COVID-19 is urgently needed. We investigated CoronaVac …
Characteristics of SARS-CoV-2 and COVID-19
B Hu, H Guo, P Zhou, ZL Shi - Nature reviews microbiology, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a highly transmissible
and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute …
and pathogenic coronavirus that emerged in late 2019 and has caused a pandemic of acute …