Acute lymphoblastic leukemia in children
SP Hunger, CG Mullighan - New England Journal of Medicine, 2015 - Mass Medical Soc
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Childhood acute lymphoblastic leukemia: progress through collaboration
CH Pui, JJ Yang, SP Hunger, R Pieters… - Journal of Clinical …, 2015 - ascopubs.org
Purpose To review the impact of collaborative studies on advances in the biology and
treatment of acute lymphoblastic leukemia (ALL) in children and adolescents. Methods A …
treatment of acute lymphoblastic leukemia (ALL) in children and adolescents. Methods A …
Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia
KG Roberts, Y Li, D Payne-Turner… - New England journal …, 2014 - Mass Medical Soc
Background Philadelphia chromosome–like acute lymphoblastic leukemia (Ph-like ALL) is
characterized by a gene-expression profile similar to that of BCR–ABL1–positive ALL …
characterized by a gene-expression profile similar to that of BCR–ABL1–positive ALL …
Acute lymphoblastic leukaemia
H Inaba, M Greaves, CG Mullighan - The Lancet, 2013 - thelancet.com
Acute lymphoblastic leukaemia occurs in both children and adults but its incidence peaks
between 2 and 5 years of age. Causation is multifactorial and exogenous or endogenous …
between 2 and 5 years of age. Causation is multifactorial and exogenous or endogenous …
The genetic basis of early T-cell precursor acute lymphoblastic leukaemia
Early T-cell precursor acute lymphoblastic leukaemia (ETP ALL) is an aggressive
malignancy of unknown genetic basis. We performed whole-genome sequencing of 12 ETP …
malignancy of unknown genetic basis. We performed whole-genome sequencing of 12 ETP …
Improved survival for children and adolescents with acute lymphoblastic leukemia between 1990 and 2005: a report from the children's oncology group
Purpose To examine population-based improvements in survival and the impact of clinical
covariates on outcome among children and adolescents with acute lymphoblastic leukemia …
covariates on outcome among children and adolescents with acute lymphoblastic leukemia …
Genetic basis of acute lymphoblastic leukemia
I Iacobucci, CG Mullighan - Journal of Clinical Oncology, 2017 - ascopubs.org
Acute lymphoblastic leukemia (ALL) is the most common childhood cancer, and despite cure
rates exceeding 90% in children, it remains an important cause of morbidity and mortality in …
rates exceeding 90% in children, it remains an important cause of morbidity and mortality in …
JAKs and STATs in immunity, immunodeficiency, and cancer
JAKs and STATs in Immunity, Immunodeficiency, and Cancer | New England Journal of Medicine
Skip to main content The New England Journal of Medicine homepage Advanced Search …
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The emerging complexity of gene fusions in cancer
Structural chromosome rearrangements may result in the exchange of coding or regulatory
DNA sequences between genes. Many such gene fusions are strong driver mutations in …
DNA sequences between genes. Many such gene fusions are strong driver mutations in …
[HTML][HTML] Genetic alterations activating kinase and cytokine receptor signaling in high-risk acute lymphoblastic leukemia
Genomic profiling has identified a subtype of high-risk B-progenitor acute lymphoblastic
leukemia (B-ALL) with alteration of IKZF1, a gene expression profile similar to BCR-ABL1 …
leukemia (B-ALL) with alteration of IKZF1, a gene expression profile similar to BCR-ABL1 …