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Therapeutic strategies for hepatitis B virus infection: towards a cure
Chronic hepatitis B virus (HBV) infection is a common cause of liver disease globally, with a
disproportionately high burden in South-East Asia. Vaccines and nucleoside or nucleotide …
disproportionately high burden in South-East Asia. Vaccines and nucleoside or nucleotide …
Targeting toll-like receptor 7/8 for immunotherapy: recent advances and prospectives
H Sun, Y Li, P Zhang, H ** agreement on chronic hepatitis …
Chronic hepatitis B: virology, natural history, current management and a glimpse at future opportunities
The host immune system plays an important role in chronic hepatitis B (CHB), both in viral
clearance and hepatocellular damage. Advances in our understanding of the natural history …
clearance and hepatocellular damage. Advances in our understanding of the natural history …
Targeting innate and adaptive immune responses to cure chronic HBV infection
Fewer than 1% of chronic hepatitis B virus infections per year are cured with antiviral
treatment. This creates a need for long-term treatment, which poses challenges for patients …
treatment. This creates a need for long-term treatment, which poses challenges for patients …
[PDF][PDF] Hepatitis B cure: from discovery to regulatory approval
The majority of persons currently treated for chronic hepatitis B require long‐term or lifelong
therapy. New inhibitors of hepatitis B virus entry, replication, assembly, or secretion and …
therapy. New inhibitors of hepatitis B virus entry, replication, assembly, or secretion and …
Current best practice in hepatitis B management and understanding long-term prospects for cure
The hepatitis B virus (HBV) is a major cause of cirrhosis and hepatocellular carcinoma
worldwide. Despite an effective vaccine, the prevalence of chronic infection remains high …
worldwide. Despite an effective vaccine, the prevalence of chronic infection remains high …