Bacterial terpenome

JD Rudolf, TA Alsup, B Xu, Z Li - Natural product reports, 2021 - pubs.rsc.org
Covering: up to mid-2020 Terpenoids, also called isoprenoids, are the largest and most
structurally diverse family of natural products. Found in all domains of life, there are over 80 …

Class II terpene cyclases: structures, mechanisms, and engineering

X Pan, JD Rudolf, LB Dong - Natural Product Reports, 2024 - pubs.rsc.org
Covering: up to July 2023 Terpene cyclases (TCs) catalyze some of the most complicated
reactions in nature and are responsible for creating the skeletons of more than 95 000 …

Biological and chemical diversity go hand in hand: Basidiomycota as source of new pharmaceuticals and agrochemicals

B Sandargo, C Chepkirui, T Cheng… - Biotechnology …, 2019 - Elsevier
The Basidiomycota constitutes the second largest higher taxonomic group of the Fungi after
the Ascomycota and comprises over 30.000 species. Mycelial cultures of Basidiomycota …

Terpene synthases in disguise: enzymology, structure, and opportunities of non-canonical terpene synthases

JD Rudolf, CY Chang - Natural product reports, 2020 - pubs.rsc.org
Covering: up to July 2019 Terpene synthases (TSs) are responsible for generating much of
the structural diversity found in the superfamily of terpenoid natural products. These elegant …

Mind the mushroom: natural product biosynthetic genes and enzymes of Basidiomycota

M Gressler, NA Löhr, T Schäfer, S Lawrinowitz… - Natural product …, 2021 - pubs.rsc.org
Covering: up to September 2020 Mushroom-forming fungi of the division Basidiomycota
have traditionally been recognised as prolific producers of structurally diverse and often …

Plant specialized metabolism: diversity of terpene synthases and their products

ME Bergman, N Dudareva - Current Opinion in Plant Biology, 2024 - Elsevier
Terpenoids are ubiquitous to all kingdoms of life and are one of the most diverse groups of
compounds, both structurally and functionally. Despite being derived from common …

Bacterial diterpene biosynthesis

JS Dickschat - Angewandte Chemie International Edition, 2019 - Wiley Online Library
This Minireview summarises recent developments in the biosynthesis of diterpenes by
diterpene synthases in bacteria. It is structured by the class of enzyme involved in the first …

Unprecedented neoverrucosane and cyathane diterpenoids with anti-neuroinflammatory activity from cultures of the culinary-medicinal mushroom Hericium erinaceus

J Wei, J Li, X Feng, Y Zhang, X Hu, H Hui, X Xue, J Qi - Molecules, 2023 - mdpi.com
The culinary medicinal mushroom Hericium erinaceus holds significant global esteem and
has garnered heightened interest within increasingly ageing societies due to its pronounced …

Four billion years of microbial terpenome evolution

Y Hoshino, L Villanueva - FEMS microbiology reviews, 2023 - academic.oup.com
Terpenoids, also known as isoprenoids, are the largest and most diverse class of organic
compounds in nature and are involved in many membrane-associated cellular processes …

Subrutilane—A Hexacyclic Sesterterpene from Streptomyces subrutilus

B Gu, B Goldfuss, G Schnakenburg… - Angewandte Chemie …, 2023 - Wiley Online Library
Mining of a terpene synthase from Streptomyces subrutilus resulted in the identification of
the hexacyclic sesterterpene subrutilane, besides eight pentacyclic side products …