Optimizing stem cell therapy after ischemic brain injury

S Zhang, BB Lachance, B Moiz, X Jia - Journal of Stroke, 2020 - pmc.ncbi.nlm.nih.gov
Stem cells have been used for regenerative and therapeutic purposes in a variety of
diseases. In ischemic brain injury, preclinical studies have been promising, but have failed …

Johnny on the spot-chronic inflammation is driven by HMGB1

CM Gorgulho, GG Romagnoli, R Bharthi… - Frontiers in …, 2019 - frontiersin.org
Although much has been made of the role of HMGB1 acting as an acute damage associated
molecular pattern (DAMP) molecule, prompting the response to tissue damage or injury, it is …

Significant clinical, neuropathological and behavioural recovery from acute spinal cord trauma by transplantation of a well-defined somatic stem cell from human …

J Schira, M Gasis, V Estrada, M Hendricks, C Schmitz… - Brain, 2012 - academic.oup.com
Stem cell therapy is a potential treatment for spinal cord injury and different stem cell types
have been grafted into animal models and humans suffering from spinal trauma. Due to …

Hepatocyte growth factor modification promotes the amelioration effects of human umbilical cord mesenchymal stem cells on rat acute kidney injury

Y Chen, H Qian, W Zhu, X Zhang, Y Yan… - Stem cells and …, 2011 - liebertpub.com
Human umbilical cord–derived mesenchymal stem cells (hucMSCs) are particularly
attractive cells for cellular and gene therapy in acute kidney injury (AKI). Adenovirus …

[HTML][HTML] The HOX Code as a “biological fingerprint” to distinguish functionally distinct stem cell populations derived from cord blood

S Liedtke, A Buchheiser, J Bosch, F Bosse, F Kruse… - Stem cell …, 2010 - Elsevier
Mesenchymal stem cells (MSC) have been isolated from almost every adult tissue. In cord
blood (CB), different non-hematopoietic CD45-, CD34− adherent cell populations can be …

Human umbilical cord blood cell transplantation in neuroregenerative strategies

LR Galieva, YO Mukhamedshina… - Frontiers in …, 2017 - frontiersin.org
At present there is no effective treatment of pathologies associated with the death of neurons
and glial cells which take place as a result of physical trauma or ischemic lesions of the …

[HTML][HTML] Cord blood transplantation and stem cell regenerative potential

Y Liao, MB Geyer, AJ Yang, MS Cairo - Experimental hematology, 2011 - Elsevier
The past 20 years of experience with umbilical cord blood transplantation have
demonstrated that cord blood is effective in the treatment of a spectrum of diseases …

DLK-1 as a marker to distinguish unrestricted somatic stem cells and mesenchymal stromal cells in cord blood

SM Kluth, A Buchheiser, AP Houben… - Stem cells and …, 2010 - liebertpub.com
In addition to hematopoietic stem cells, cord blood (CB) also contains different
nonhematopoietic CD45−, CD34− adherent cell populations: cord blood mesenchymal …

Hepatocyte growth factor-modified mesenchymal stem cells improve ischemia/reperfusion-induced acute lung injury in rats

S Chen, X Chen, X Wu, S Wei, W Han, J Lin, M Kang… - Gene therapy, 2017 - nature.com
Accumulative evidence demonstrated that mesenchymal stem cell (MSC) engraftment could
protect tissue injury from ischemia/reperfusion (I/R). Hepatocyte growth factor (HGF) has …

Mesenchymal stem cell printing and process regulated cell properties

J Snyder, AR Son, Q Hamid, C Wang, Y Lui… - Biofabrication, 2015 - iopscience.iop.org
This topical review with original analysis and empirical results compares cell sensitivity to
physical stress during printing. The objective is to frame a reproducible causation between …