α-Lipoic acid, which plays an essential role in mitochondrial dehydrogenase reactions, has
recently gained considerable attention as an antioxidant. Lipoate, or its reduced form …

Carbon monoxide (CO) is continuously produced in mammalian cells during the
degradation of heme. It is a stable gaseous molecule that reacts selectively with transition …

Reactive oxygen (ROS) and nitrogen oxide (RNOS) species are produced as by-products of
oxidative metabolism. A major function for ROS and RNOS is immunological host defense …

R-α-Lipoic acid is found naturally occurring as a prosthetic group in α-keto acid
dehydrogenase complexes of the mitochondria, and as such plays a fundamental role in …

Meat colour is a major factor that influences the purchase decision by consumers. Many
intrinsic and extrinsic factors contribute to the final colour of meat. The role of the MetMb …

An overview of myoglobin-initiated lipid oxidation in simple model systems, muscle, and
muscle-based foods is presented. The potential role of myoglobin spin and redox states in …

The biological effects of S-nitrosothiols have been attributed to homolytic cleavage of the SN
bond with release of nitric oxide (NO.). Rates of NO. release from several S-nitrosothiols …

The first example of a biocatalytic strategy for the synthesis of thioethers via an
intermolecular carbene S–H insertion reaction is reported. Engineered variants of sperm …

Increased oxidative stress and impaired antioxidant defense mechanisms are important
factors in the pathogenesis and progression of diabetes mellitus and other oxidant-related …

Hydrogen sulfide is now a well-appreciated master regulator in a diverse array of
physiological processes. However, as a consequence of the rapid growth of the area, sulfide …