Recent advances in directed sp 2 C–H functionalization towards the synthesis of N-heterocycles and O-heterocycles
Heterocyclic compounds are widely present in the core structures of several natural
products, pharmaceuticals and agrochemicals, and thus great efforts have been devoted to …
products, pharmaceuticals and agrochemicals, and thus great efforts have been devoted to …
Isoindolinone Synthesis via One‐Pot Type Transition Metal Catalyzed C− C Bond Forming Reactions
R Savela, C Méndez‐Gálvez - Chemistry–A European Journal, 2021 - Wiley Online Library
Isoindolinone structure is an important privileged scaffold found in a large variety of naturally
occurring as well as synthetic, biologically and pharmaceutically active compounds. Owing …
occurring as well as synthetic, biologically and pharmaceutically active compounds. Owing …
Free Amine and Alcohol As the Director for Regioselective C(sp2)–H Bond Functionalization
Transition-metal-catalyzed C (sp2)–H bond functionalization is recognized as a
revolutionized strategy for mainstream organic synthesis to forge structurally complex …
revolutionized strategy for mainstream organic synthesis to forge structurally complex …
Visible-light-photocatalyzed synthesis of phenanthridinones and quinolinones via direct oxidative C–H amidation
A straightforward synthetic strategy to construct biologically relevant phenanthridinones and
quinolinones was developed via visible-light-promoted direct oxidative C–H amidation. In …
quinolinones was developed via visible-light-promoted direct oxidative C–H amidation. In …
Transition metal-free photocatalytic radical annulation of 2-cyanoaryl acrylamides with difluoromethyl radicals to assemble 4-amino-quinolinone derivatives
Q Wu, N Zhang, X Gong, M Ren, Y Xu, Y Chen - Green Chemistry, 2023 - pubs.rsc.org
The transformation of an iminyl radical into a primary amine is a challenging task. A practical
and green catalytic system to trigger difluoromethyl radicals is highly desired. Herein, we …
and green catalytic system to trigger difluoromethyl radicals is highly desired. Herein, we …
Metal‐Catalyzed Synthesis of Substituted Indoles
Indoles are important structural motifs that are commonly found in a diverse array of natural
products, pharmaceuticals, and other functional molecules. Consequently, the development …
products, pharmaceuticals, and other functional molecules. Consequently, the development …
Metal-Free Boron-Mediated ortho-C–H Hydroxylation of N-Benzyl-3,4,5-tribromopyrazoles
G Wu, Z Yang, X Xu, L Hao, L Chen, Y Wang… - Organic Letters, 2022 - ACS Publications
A novel route has been reported for C–H hydroxylation of benzyl compounds directed by a
3, 4, 5-tribromopyrazole auxiliary via boronation/oxidation using BBr3 and NaBO3· 4H2O …
3, 4, 5-tribromopyrazole auxiliary via boronation/oxidation using BBr3 and NaBO3· 4H2O …
Radical annulation of 2-cyanoaryl acrylamides via C═ C double bond cleavage: access to amino-substituted 2-quinolones
WJ **a, TG Fan, ZW Zhao, X Chen, XX Wang… - Organic …, 2021 - ACS Publications
A novel annulation of 2-cyanoaryl acrylamides via C═ C double bond cleavage has been
developed for facile and efficient access to a broad spectrum of functionalized 4-amino-2 …
developed for facile and efficient access to a broad spectrum of functionalized 4-amino-2 …
Transition metal-catalyzed synthesis of N, O− Heterocycles via C–H functionalization
T Naveen - Tetrahedron, 2021 - Elsevier
Heterocyclic compounds are widely present in the core structures of several natural
products, pharmaceuticals, and agrochemicals. Over the years, synthesis of heterocyclic …
products, pharmaceuticals, and agrochemicals. Over the years, synthesis of heterocyclic …
Palladium Catalysis: Dependence of the Efficiency of C− C Bond Formation on Carboxylate Ligand and Alkali Metal Carboxylate or Carboxylic Acid Additive. Part A …
J Le Bras, J Muzart - Advanced Synthesis & Catalysis, 2023 - Wiley Online Library
A variety of Pd‐catalyzed reactions are carried out with palladium carboxylates in the
presence of carboxylic acids and/or alkali metal carboxylates. This review is Part A of three …
presence of carboxylic acids and/or alkali metal carboxylates. This review is Part A of three …