An overview of mucosa-associated protozoa: challenges in chemotherapy and future perspectives
HLC Santos, KM Rebello - Frontiers in Cellular and Infection …, 2022 - frontiersin.org
Parasitic infections caused by protozoans that infect the mucosal surfaces are widely
neglected worldwide. Collectively, Entamoeba histolytica, Giardia lamblia, Cryptosporidium …
neglected worldwide. Collectively, Entamoeba histolytica, Giardia lamblia, Cryptosporidium …
What place does molecular topology have in today's drug discovery?
Introduction Most methods in molecular and drug design are currently based on
physicochemical descriptors. However, molecular topology, which relies on topological …
physicochemical descriptors. However, molecular topology, which relies on topological …
Ensemble models based on QuBiLS-MAS features and shallow learning for the prediction of drug-induced liver toxicity: improving deep learning and traditional …
Drug-induced liver injury (DILI) is a key safety issue in the drug discovery pipeline and a
regulatory concern. Thus, many in silico tools have been proposed to improve the …
regulatory concern. Thus, many in silico tools have been proposed to improve the …
Cell Membrane-Coated Nanoparticles for Management of Infectious Diseases: A Review
L Sun, M Li, J Yang, J Li - Industrial & Engineering Chemistry …, 2022 - ACS Publications
Infectious diseases have emerged as leading threats to global healthcare, such as bacterial
and viral infections. Major challenges in combating these infectious diseases are the …
and viral infections. Major challenges in combating these infectious diseases are the …
Enhancing acute oral toxicity predictions by using consensus modeling and algebraic form-based 0D-to-2D molecular encodes
Quantitative structure–activity relationships (QSAR) are introduced to predict acute oral
toxicity (AOT), by using the QuBiLS-MAS (acronym for quadratic, bilinear and N-Linear maps …
toxicity (AOT), by using the QuBiLS-MAS (acronym for quadratic, bilinear and N-Linear maps …
Overproduce and select, or determine optimal molecular descriptor subset via configuration space optimization? Application to the prediction of ecotoxicological …
Predicting the likely biological activity (or property) of compounds is a fundamental and
challenging task in the drug discovery process. Current computational methodologies aim to …
challenging task in the drug discovery process. Current computational methodologies aim to …
Revealing the progression and pathologic features of intraperitoneal infection of Trichomonas vaginalis in mice via parasite α-actinin-based immunological detection
Background Trichomoniasis caused by Trichomonas vaginalis is the most prevalent nonviral
sexually transmitted disease in women and has frequently damaged public health. To better …
sexually transmitted disease in women and has frequently damaged public health. To better …
Choquet integral-based fuzzy molecular characterizations: when global definitions are computed from the dependency among atom/bond contributions (LOVIs/LOEIs)
CR García-Jacas, L Cabrera-Leyva… - Journal of …, 2018 - Springer
Background Several topological (2D) and geometric (3D) molecular descriptors (MDs) are
calculated from local vertex/edge invariants (LOVIs/LOEIs) by performing an aggregation …
calculated from local vertex/edge invariants (LOVIs/LOEIs) by performing an aggregation …
[PDF][PDF] " DEEP BLOCK": NEW THERAPEUTIC ALTERNATIVE WITH SCIENTIFIC BASIS FOR THE SUCCESSFUL CONTROL OF “COVID-19” IN ALL PHASES OF THE …
VHC Rodríguez, E Morales, MG Morales, J Martínez… - researchgate.net
From the 1940s to the present, approximately 49% of all medicines approved by the WHO
are composed of active substances of natural origin or direct derivatives thereof. About 75 …
are composed of active substances of natural origin or direct derivatives thereof. About 75 …
[CITATION][C] Trichomonas vaginalis y tricomoniasis
M Martínez Pérez - 2020