Lymphoid organ-targeted nanomaterials for immunomodulation of cancer, inflammation, and beyond

JC Hsu, P Liu, Y Song, W Song, RJ Saladin… - Chemical Society …, 2024 - pubs.rsc.org
Nanomaterials exhibit significant potential for stimulating immune responses, offering both
local and systemic modulation across a variety of diseases. The lymphoid organs, such as …

Intrinsic immunomodulatory hydrogels for chronic inflammation

Y Qian, J Ding, R Zhao, Y Song, J Yoo… - Chemical Society …, 2025 - pubs.rsc.org
The immune system plays a pivotal role in maintaining physiological homeostasis and
influencing disease processes. Dysregulated immune responses drive chronic inflammation …

New opportunities for immunomodulation of the tumour microenvironment using chemical tools

JY Su, WH Li, YM Li - Chemical Society Reviews, 2022 - pubs.rsc.org
Immunotherapy is recognised as an attractive method for the treatment of cancer, and
numerous treatment strategies have emerged over recent years. Investigations of the tumour …

Synthetic High‐Density Lipoprotein‐Based Nanomedicine to Silence SOCS1 in Tumor Microenvironment and Trigger Antitumor Immunity against Glioma

C Yang, Y Li, Y Yang, Q Ni, Z Zhang… - Angewandte Chemie …, 2023 - Wiley Online Library
Immunotherapies have shed light on the treatment of many cancers, but have not improved
the outcomes of glioma (GBM). Here, we demonstrated that suppressor of cytokine signaling …

High-density lipoproteins: A promising tool against cancer

A Ossoli, A Wolska, AT Remaley… - Biochimica et Biophysica …, 2022 - Elsevier
High-density lipoproteins (HDL) are well known for their protective role against the
development and progression of atherosclerosis. Atheroprotection is mainly due to the key …

A modular approach toward producing nanotherapeutics targeting the innate immune system

MMT van Leent, AE Meerwaldt, A Berchouchi… - Science …, 2021 - science.org
Immunotherapies controlling the adaptive immune system are firmly established, but
regulating the innate immune system remains much less explored. The intrinsic interactions …

Neutrophil metabolism in the cancer context

A Bodac, E Meylan - Seminars in immunology, 2021 - Elsevier
Neutrophils are critical innate immune cells for the host anti-bacterial defense. Throughout
their lifecycle, neutrophils are exposed to different microenvironments and modulate their …

Targeting the innate immune system with nanoparticles for cancer immunotherapy

K Li, Z Zhang, Y Mei, M Li, Q Yang, Q Wu… - Journal of Materials …, 2022 - pubs.rsc.org
Various cancer therapies have advanced remarkably over the past decade. Unlike the direct
therapeutic targeting of tumor cells, cancer immunotherapy is a new strategy that boosts the …

Intravital microscopy for real-time monitoring of drug delivery and nanobiological processes

J Momoh, D Kapsokalyvas, M Vogt, S Hak… - Advanced Drug Delivery …, 2022 - Elsevier
Intravital microscopy (IVM) expands our understanding of cellular and molecular processes,
with applications ranging from fundamental biology to (patho) physiology and immunology …

[HTML][HTML] Differential structure and immunomodulatory functions of lipophosphoglycan between Leishmania spp

LU Teufel, LAB Joosten, JC Dos Santos - Immunology Letters, 2024 - Elsevier
Leishmaniasis is a collective term for several tropical, neglected diseases caused by
protozoans of the species Leishmania, 20 of which causing disease in humans ranging from …