[HTML][HTML] The world federation of ADHD international consensus statement: 208 evidence-based conclusions about the disorder

SV Faraone, T Banaschewski, D Coghill… - … & biobehavioral reviews, 2021 - Elsevier
Background Misconceptions about ADHD stigmatize affected people, reduce credibility of
providers, and prevent/delay treatment. To challenge misconceptions, we curated findings …

Genomics, convergent neuroscience and progress in understanding autism spectrum disorder

HR Willsey, AJ Willsey, B Wang… - Nature Reviews …, 2022 - nature.com
More than a hundred genes have been identified that, when disrupted, impart large risk for
autism spectrum disorder (ASD). Current knowledge about the encoded proteins—although …

The molecular cytoarchitecture of the adult mouse brain

J Langlieb, NS Sachdev, KS Balderrama, NM Nadaf… - Nature, 2023 - nature.com
The function of the mammalian brain relies upon the specification and spatial positioning of
diversely specialized cell types. Yet, the molecular identities of the cell types and their …

Polygenic architecture of rare coding variation across 394,783 exomes

DJ Weiner, A Nadig, KA Jagadeesh, KK Dey, BM Neale… - Nature, 2023 - nature.com
Both common and rare genetic variants influence complex traits and common diseases.
Genome-wide association studies have identified thousands of common-variant …

Psychiatric diagnosis and treatment in the 21st century: paradigm shifts versus incremental integration

DJ Stein, SJ Shoptaw, DV Vigo, C Lund… - World …, 2022 - Wiley Online Library
Psychiatry has always been characterized by a range of different models of and approaches
to mental disorder, which have sometimes brought progress in clinical practice, but have …

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

N Mullins, AJ Forstner, KS O'Connell, B Coombes… - Nature …, 2021 - nature.com
Bipolar disorder is a heritable mental illness with complex etiology. We performed a genome-
wide association study of 41,917 bipolar disorder cases and 371,549 controls of European …

Genomic findings in schizophrenia and their implications

MJ Owen, SE Legge, E Rees, JTR Walters… - Molecular …, 2023 - nature.com
There has been substantial progress in understanding the genetics of schizophrenia over
the past 15 years. This has revealed a highly polygenic condition with the majority of the …

Obesity as a multisystem disease: Trends in obesity rates and obesity‐related complications

S Sarma, S Sockalingam, S Dash - Diabetes, Obesity and …, 2021 - Wiley Online Library
Obesity is a chronic multisystem disease associated with increased morbidity and mortality.
The increasing prevalence of obesity makes it a major healthcare challenge across both …

Comorbid depression in medical diseases

SM Gold, O Köhler-Forsberg, R Moss-Morris… - Nature reviews Disease …, 2020 - nature.com
Depression is one of the most common comorbidities of many chronic medical diseases
including cancer and cardiovascular, metabolic, inflammatory and neurological disorders …

[HTML][HTML] Pharmacotherapy of anxiety disorders: current and emerging treatment options

A Garakani, JW Murrough, RC Freire, RP Thom… - Frontiers in …, 2020 - frontiersin.org
Anxiety disorders are the most prevalent psychiatric disorders and a leading cause of
disability. While there continues to be expansive research in posttraumatic stress disorder …