As the crucial powerhouse for cell metabolism and tissue survival, the mitochondrion
frequently undergoes morphological or positional changes when responding to various …

Mitochondria are the powerhouse of cells. They are vital organelles that maintain cellular
function and metabolism. Dysfunction of mitochondria results in various diseases with a …

Mitochondria, which play central roles in immunometabolic diseases, have their own
genome. However, the functions of mitochondria-located noncoding RNAs are largely …

Mammalian genes were long thought to be constrained within somatic cells in most cell
types. This concept was challenged recently when cellular organelles including …

Mitochondria are subject to unique genetic control by both nuclear DNA and their own
genome, mitochondrial DNA (mtDNA), of which each mitochondrion contains multiple …

In recent years mitochondrial DNA (mtDNA) has transitioned to greater prominence across
diverse areas of biology and medicine. The recognition of mitochondria as a major …

Mitochondria regulate multiple cell processes, including calcium signaling, apoptosis and
cell metabolism. Mitochondria contain their own circular genome encoding selected …

Recently, we showed that generation of tumours in syngeneic mice by cells devoid of
mitochondrial (mt) DNA (ρ0 cells) is linked to the acquisition of the host mtDNA. However …

Highly precise micromanipulation tools that can manipulate and interrogate cell organelles
and components must be developed to support the rapid development of new cell-based …

Neurons and glia maintain central nervous system (CNS) homeostasis through diverse
mechanisms of intra-and intercellular signaling. Some of these interactions include the …