After the discovery of zinc deficiency in the 1960s, it soon became clear that zinc is essential
for the function of the immune system. Zinc ions are involved in regulating intracellular …

Zinc is a ubiquitous biological metal in all living organisms. The spatiotemporal zinc
dynamics in cells provide crucial cellular signaling opportunities, but also challenges for …

Zinc is involved in a variety of biological processes, as a structural, catalytic, and intracellular
and intercellular signaling component. Thus zinc homeostasis is tightly controlled at the …

Zinc (Zn) is an essential trace mineral that regulates the expression and activation of
biological molecules such as transcription factors, enzymes, adapters, channels, and growth …

Metals are essential components in all forms of life required for the function of nearly half of
all enzymes and are critically involved in virtually all fundamental biological processes …

Zinc (Zn) nutritional importance has been known for a long time, but in the last decades its
importance in immune modulation has arisen. This review aims at describing the …

Around 3000 proteins are thought to bind zinc in vivo, which corresponds to~ 10% of the
human proteome. Zinc plays a pivotal role as a structural, catalytic, and signaling component …

Zinc (Zn) is an essential micronutrient for basic cell activities such as cell growth,
differentiation, and survival. Zn deficiency depresses both innate and adaptive immune …

Zinc is an essential micronutrient that plays a role in the structural or enzymatic functions of
many cellular proteins. Cellular zinc homeostasis involves the opposing action of two …

The essential trace element zinc (Zn) is widely required in cellular functions, and abnormal
Zn homeostasis causes a variety of health problems that include growth retardation …