[HTML][HTML] Recent developments in frailty identification, management, risk factors and prevention: a narrative review of leading journals in geriatrics and gerontology

E Dent, P Hanlon, M Sim, J Jylhävä, Z Liu… - Ageing Research …, 2023 - Elsevier
Frailty is an age-related clinical condition characterised by an increased susceptibility to
stressors and an elevated risk of adverse outcomes such as mortality. In the light of global …

[HTML][HTML] Aging, sex, metabolic and life experience factors: Contributions to neuro-inflammaging in Alzheimer's disease research

PH Singhaarachchi, P Antal, F Calon… - Neuroscience & …, 2024 - Elsevier
Alzheimer's disease (AD) is prevalent around the world, yet our understanding of the
disease is still very limited. Recent work suggests that the cornerstone of AD may include the …

Unraveling the metabolic underpinnings of frailty using multicohort observational and Mendelian randomization analyses

JKL Mak, L Kananen, C Qin, R Kuja‐Halkola… - Aging …, 2023 - Wiley Online Library
Identifying metabolic biomarkers of frailty, an age‐related state of physiological decline, is
important for understanding its metabolic underpinnings and develo** preventive …

Frailty and the risk of dementia: is the association explained by shared environmental and genetic factors?

G Bai, Y Wang, R Kuja-Halkola, X Li, Y Tomata… - BMC medicine, 2021 - Springer
Background Frailty has been identified as a risk factor for cognitive impairment and
dementia. However, it is not known whether familial factors, such as genetics and shared …

Genetic and environmental influences on longitudinal frailty trajectories from adulthood into old age

JKL Mak, R Kuja-Halkola, G Bai… - The Journals of …, 2023 - academic.oup.com
Background Frailty is a complex, dynamic geriatric condition, but limited evidence has
shown how genes and environment may contribute to its longitudinal changes. We sought to …

[HTML][HTML] Frailty and associated factors among Chinese centenarians

J Zhang, L Xu - The Journal of nutrition, health and aging, 2022 - Elsevier
Objectives The study aimed to apply the frailty index (FI) to assess frailty status among
Chinese centenarians and analyse its associated factors. Design The study was a cross …

[HTML][HTML] Characterization by gender of frailty syndrome in elderly people according to frail trait scale and fried frailty phenotype

I Palomo, F García, C Albala, S Wehinger… - Journal of Personalized …, 2022 - mdpi.com
Background: Frailty has emerged as one of the main geriatric syndromes to be prevented in
order to improve quality of health and life in the elderly. In this sense, the characterization of …

A genetically informed study of digital screen time, video game play, and impulsivity in established adulthood

A Zheng, S Pahlen, TT Vo, F Lawrence… - Computers in Human …, 2024 - Elsevier
High levels of digital screen time are associated with heightened impulsivity, though the
assumption that this relationship is causal has seldom been rigorously examined. Moreover …

Secular trends in frailty among community-dwelling 75–95-year-old cohorts over three decades in Helsinki, Finland

KH Pitkälä, UL Aalto, HM Roitto, HR Öhman… - Age and …, 2024 - academic.oup.com
Abstract Background Frailty Index (FI) reflects health, functioning and well-being of older
people. It is valuable to compare how frailty has changed over time in ageing cohorts. This …

The association between chronic heart failure and frailty index: a study based on the National Health and Nutrition Examination Survey from 1999 to 2018

X Chen, C Hou, L Yao, Y Ma, Y Li, J Li, M Gui… - Frontiers in …, 2023 - frontiersin.org
Objective This study aims to explore the association between the frailty index and chronic
heart failure (CHF). Methods We collected data from the National Health and Nutrition …