A review: Pharmacological aspects of metal based 1, 2, 4-triazole derived Schiff bases

W Zafar, SH Sumrra, ZH Chohan - European journal of medicinal chemistry, 2021 - Elsevier
Clinical reports have highlighted the radical increase of antibiotic resistance. As a result,
multidrug resistance has emerged as a serious threat to human health. Many organic …

Metallodrugs in medicinal inorganic chemistry

KD Mjos, C Orvig - Chemical reviews, 2014 - ACS Publications
Metal ions play important roles in biological processes, 1 and the field of knowledge
concerned with the application of inorganic chemistry to therapy or diagnosis of disease is …

Advances in copper complexes as anticancer agents

C Santini, M Pellei, V Gandin, M Porchia… - Chemical …, 2014 - ACS Publications
Medicinal inorganic chemistry offers additional opportunities for the design of therapeutic
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …

Vanadium compounds in medicine

JC Pessoa, S Etcheverry, D Gambino - Coordination chemistry reviews, 2015 - Elsevier
Vanadium is a transition metal that, being ubiquitously distributed in soil, crude oil, water
and air, also found roles in biological systems and is an essential element in most living …

Advancement of metal compounds as therapeutic and diagnostic metallodrugs: Current frontiers and future perspectives

I Yousuf, M Bashir, F Arjmand, S Tabassum - Coordination Chemistry …, 2021 - Elsevier
Coordination compounds on account of distinctive features of metal ions that include
variable oxidation states, diverse range of geometries and coordination numbers …

Fluoro-and chromogenic chemodosimeters for heavy metal ion detection in solution and biospecimens

DT Quang, JS Kim - Chemical reviews, 2010 - ACS Publications
Heavy metal ions are of great concern, not only among the scientific community, especially
chemists, biologists, and environmentalists, but increasingly among the general population …

Novel metals and metal complexes as platforms for cancer therapy

M Frezza, S Hindo, D Chen, A Davenport… - Current …, 2010 - benthamdirect.com
Metals are essential cellular components selected by nature to function in several
indispensable biochemical processes for living organisms. Metals are endowed with unique …

New trends for metal complexes with anticancer activity

PCA Bruijnincx, PJ Sadler - Current opinion in chemical biology, 2008 - Elsevier
Medicinal inorganic chemistry can exploit the unique properties of metal ions for the design
of new drugs. This has, for instance, led to the clinical application of chemotherapeutic …

New metal complexes as potential therapeutics

CX Zhang, SJ Lippard - Current opinion in chemical biology, 2003 - Elsevier
The many activities of metal ions in biology have stimulated the development of metal-based
therapeutics. Cisplatin, as one of the leading metal-based drugs, is widely used in treatment …

Syntheses, structural characterization, and cytotoxicity assessment of novel Mn (II) and Zn (II) complexes of aroyl-hydrazone Schiff base Ligand

M Bashir, AA Dar, I Yousuf - ACS omega, 2023 - ACS Publications
This work describes the syntheses, structural characterization, and biological profile of Mn
(II)-and Zn (II)-based complexes 1 and 2 derived from the aroyl-hydrazone Schiff base ligand …