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A review: Pharmacological aspects of metal based 1, 2, 4-triazole derived Schiff bases
Clinical reports have highlighted the radical increase of antibiotic resistance. As a result,
multidrug resistance has emerged as a serious threat to human health. Many organic …
multidrug resistance has emerged as a serious threat to human health. Many organic …
Metallodrugs in medicinal inorganic chemistry
KD Mjos, C Orvig - Chemical reviews, 2014 - ACS Publications
Metal ions play important roles in biological processes, 1 and the field of knowledge
concerned with the application of inorganic chemistry to therapy or diagnosis of disease is …
concerned with the application of inorganic chemistry to therapy or diagnosis of disease is …
Advances in copper complexes as anticancer agents
Medicinal inorganic chemistry offers additional opportunities for the design of therapeutic
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …
agents not accessible to organic compounds. 1− 3 The wide range of coordination numbers …
Vanadium compounds in medicine
Vanadium is a transition metal that, being ubiquitously distributed in soil, crude oil, water
and air, also found roles in biological systems and is an essential element in most living …
and air, also found roles in biological systems and is an essential element in most living …
Advancement of metal compounds as therapeutic and diagnostic metallodrugs: Current frontiers and future perspectives
Coordination compounds on account of distinctive features of metal ions that include
variable oxidation states, diverse range of geometries and coordination numbers …
variable oxidation states, diverse range of geometries and coordination numbers …
Fluoro-and chromogenic chemodosimeters for heavy metal ion detection in solution and biospecimens
Heavy metal ions are of great concern, not only among the scientific community, especially
chemists, biologists, and environmentalists, but increasingly among the general population …
chemists, biologists, and environmentalists, but increasingly among the general population …
Novel metals and metal complexes as platforms for cancer therapy
M Frezza, S Hindo, D Chen, A Davenport… - Current …, 2010 - benthamdirect.com
Metals are essential cellular components selected by nature to function in several
indispensable biochemical processes for living organisms. Metals are endowed with unique …
indispensable biochemical processes for living organisms. Metals are endowed with unique …
New trends for metal complexes with anticancer activity
PCA Bruijnincx, PJ Sadler - Current opinion in chemical biology, 2008 - Elsevier
Medicinal inorganic chemistry can exploit the unique properties of metal ions for the design
of new drugs. This has, for instance, led to the clinical application of chemotherapeutic …
of new drugs. This has, for instance, led to the clinical application of chemotherapeutic …
New metal complexes as potential therapeutics
CX Zhang, SJ Lippard - Current opinion in chemical biology, 2003 - Elsevier
The many activities of metal ions in biology have stimulated the development of metal-based
therapeutics. Cisplatin, as one of the leading metal-based drugs, is widely used in treatment …
therapeutics. Cisplatin, as one of the leading metal-based drugs, is widely used in treatment …
Syntheses, structural characterization, and cytotoxicity assessment of novel Mn (II) and Zn (II) complexes of aroyl-hydrazone Schiff base Ligand
This work describes the syntheses, structural characterization, and biological profile of Mn
(II)-and Zn (II)-based complexes 1 and 2 derived from the aroyl-hydrazone Schiff base ligand …
(II)-and Zn (II)-based complexes 1 and 2 derived from the aroyl-hydrazone Schiff base ligand …