Secrets from immortal worms: What can we learn about biological ageing from the planarian model system?

S Sahu, A Dattani, AA Aboobaker - Seminars in cell & developmental …, 2017 - Elsevier
Understanding how some animals are immortal and avoid the ageing process is important.
We currently know very little about how they achieve this. Research with genetic model …

[BOEK][B] The first brain: the neuroscience of planarians

OR Pagán - 2014 - books.google.com
Planarians, a class of flatworm, are extraordinary: they possess the remarkable ability to
regenerate lost body parts, including complete regeneration of the nervous system. If cut into …

[HTML][HTML] Planarian MBD2/3 is required for adult stem cell pluripotency independently of DNA methylation

F Jaber-Hijazi, PJKP Lo, Y Mihaylova, JM Foster… - Developmental …, 2013 - Elsevier
Planarian adult stem cells (pASCs) or neoblasts represent an ideal system to study the
evolution of stem cells and pluripotency as they underpin an unrivaled capacity for …

The CCR4-NOT complex mediates deadenylation and degradation of stem cell mRNAs and promotes planarian stem cell differentiation

J Solana, C Gamberi, Y Mihaylova, S Grosswendt… - PLoS …, 2013 - journals.plos.org
Post-transcriptional regulatory mechanisms are of fundamental importance to form robust
genetic networks, but their roles in stem cell pluripotency remain poorly understood. Here …

An Introduction to planarians and their stem cells

E Aboukhatwa, A Aboobaker - eLS, 2015 - Wiley Online Library
Of all animals, it is perhaps planarians that have the greatest ability to regenerate. These
once classical classroom organisms have now become the subject of advanced molecular …

Comparative Genomics Identifies Conserved Factors that Regulate Stemness in Adult and Cancer Stem Cells

M Wiggans - 2023 - search.proquest.com
Adult stem cells (ASCs) that self renew indefinitely and generate differentiated cell types are
present in species of every phylum identified and, thus, likely share a common evolutionary …

Stammzellen I: Basiswissen updated: Geborgen aus einer riesigen Informationsflut

WA Müller - Biologie in unserer Zeit, 2012 - Wiley Online Library
Stammzellen wurden erstmals 1883 von A. Weismann als Urkeimzellen, das heißt als
Stammzellen der Keimzellen, beschrieben und so benannt. Im gesamten Tierreich sind …

An investigation of cellular and molecular mechanisms of stem cell regulation in Schmidtea mediterranea

E Aboukhatwa - 2015 - ora.ox.ac.uk
The planarian Schmidtea mediterranea discovered by Benazzi, Baguñà, Ballester,
Puccinelli & Del Papa, 1975 is a classic model organism for the investigation of regenerative …

[PDF][PDF] cell pluripotency independently of DNA methylation. Developmental Biology, 384 (1). pp. 141-153. ISSN 0012-1606

F Jaber-Hijazi - Developmental Biology, 2013 - academia.edu
abstract Planarian adult stem cells (pASCs) or neoblasts represent an ideal system to study
the evolution of stem cells and pluripotency as they underpin an unrivaled capacity for …