Understanding the Biology and Immune Pathogenesis of Chikungunya Virus Infection for Diagnostic and Vaccine Development

MS Hakim, AT Aman - Viruses, 2022 - mdpi.com
Chikungunya virus, the causative agent of chikungunya fever, is generally characterized by
the sudden onset of symptoms, including fever, rash, myalgia, and headache. In some …

Histopathological and immunological characteristics of placentas infected with chikungunya virus

N Salomão, K Rabelo, E Avvad-Portari… - Frontiers in …, 2022 - frontiersin.org
Although vertical transmission of CHIKV has been reported, little is known about the role of
placenta in the transmission of this virus and the effects of infection on the maternal-fetal …

[HTML][HTML] Pathogenesis and clinical management of arboviral diseases

VC Dietrich, JMC Costa, MMGL Oliveira… - World Journal of …, 2025 - wjgnet.com
Arboviral diseases are viral infections transmitted to humans through the bites of arthropods,
such as mosquitoes, often causing a variety of pathologies associated with high levels of …

Diagnostic accuracy of DPP Fever Panel II Asia tests for tropical fever diagnosis

S Dhawan, S Dittrich, S Arafah… - PLOS Neglected …, 2024 - journals.plos.org
Background Fever is the most frequent symptom in patients seeking care in South and
Southeast Asia. The introduction of rapid diagnostic tests (RDTs) for malaria continues to …

Performance Evaluation of VIDAS® Diagnostic Assays Detecting Anti-Chikungunya Virus IgM and IgG Antibodies: An International Study

GM Pereira, ER Manuli, L Coulon, MF Côrtes… - Diagnostics, 2023 - mdpi.com
Chikungunya (CHIK) is a debilitating mosquito-borne disease with an epidemiology and
early clinical symptoms similar to those of other arboviruses-triggered diseases such as …

The TIRS trial: Enrollment procedures and baseline characterization of a pediatric cohort to quantify the epidemiologic impact of targeted indoor residual spraying on …

JT Earnest, OD Kirstein, AC Mendoza… - Plos one, 2024 - journals.plos.org
Aedes mosquito-borne viruses (ABVs) place a substantial strain on public health resources
in the Americas. Vector control of Aedes mosquitoes is an important public health strategy to …

A rapid, specific and ultrasensitive detection of the Chikungunya virus based on RT-RPA: CRISPR/Cas12a one-pot dual mode end-point detection system

P Bhardwaj, S Gulafshan, R Singh - Analytica Chimica Acta, 2024 - Elsevier
Background Chikungunya (CHIK) is an underdiagnosed acute febrile illness (AFI) and an
important cause of acute encephalitis syndrome (AES). Unavailaibility of rapid and sensitive …

Development and evaluation of recombinant E2 protein based IgM capture enzyme-linked immunosorbent assay (ELISA) and double antigen sandwich ELISA for …

M Guo, S Du, L Lai, W Wu, X Huang, A Li… - PLOS Neglected …, 2022 - journals.plos.org
Background Chikungunya virus (CHIKV) reemerged and caused millions of human
infections since 2004. The disease could be established, when the virus has been …

Detection of Chikungunya Virus RNA in Oral Fluid and Urine: An Alternative Approach to Diagnosis?

LC Jacob-Nascimento, MM Portilho, RO Anjos… - Viruses, 2024 - mdpi.com
To evaluate whether oral fluids (OF) and urine can serve as alternative, non-invasive
samples to diagnose chikungunya virus (CHIKV) infection via RT-qPCR, we employed the …

[HTML][HTML] Rapid and specific detection of nanoparticles and viruses one at a time using microfluidic laminar flow and confocal fluorescence microscopy

P Drori, O Mouhadeb, GGM Muñoz, Y Razvag… - Iscience, 2024 - cell.com
Mainstream virus detection relies on the specific amplification of nucleic acids via
polymerase chain reaction, a process that is slow and requires extensive laboratory …