[HTML][HTML] Polyphenols as potent epigenetics agents for cancer

P Rajendran, SA Abdelsalam, K Renu… - International journal of …, 2022 - mdpi.com
Human diseases such as cancer can be caused by aberrant epigenetic regulation.
Polyphenols play a major role in mammalian epigenome regulation through mechanisms …

Antioxidant, anti‐inflammatory and epigenetic potential of curcumin in Alzheimer's disease

T Abdul‐Rahman, WA Awuah, T Mikhailova… - …, 2024 - Wiley Online Library
Alzheimer's disease (AD) constitutes a multifactorial neurodegenerative pathology
characterized by cognitive deterioration, personality alterations, and behavioral shifts. The …

[HTML][HTML] Omics technologies improving breast cancer research and diagnostics

A Orsini, C Diquigiovanni, E Bonora - International Journal of Molecular …, 2023 - mdpi.com
Breast cancer (BC) has yielded approximately 2.26 million new cases and has caused
nearly 685,000 deaths worldwide in the last two years, making it the most common …

[HTML][HTML] Risk factors for the development of cancers

M Poudineh, S Poudineh, Z Hosseini, S Pouramini… - Kindle, 2023 - preferpub.org
Multiple risk factors are for all types of cancers. These include endogenous factors and
exogenous factors. The main constitutional and environmental risk factors are well clarified …

Epigenetic regulation in breast cancer: insights on epidrugs

A Kim, K Mo, H Kwon, S Choe, M Park, W Kwak… - Epigenomes, 2023 - mdpi.com
Breast cancer remains a common cause of cancer-related death in women. Therefore,
further studies are necessary for the comprehension of breast cancer and the revolution of …

Role of epigenetic modulation in neurodegenerative diseases: implications of phytochemical interventions

MI Prasanth, BS Sivamaruthi, CSY Cheong, K Verma… - Antioxidants, 2024 - mdpi.com
Epigenetics defines changes in cell function without involving alterations in DNA sequence.
Neuroepigenetics bridges neuroscience and epigenetics by regulating gene expression in …

Moroccan medicinal plants used to treat cancer: ethnomedicinal study and insights into pharmacological evidence

N El Hachlafi, N Benkhaira, M Ferioun… - Evidence‐Based …, 2022 - Wiley Online Library
Cancer is one of the major medical challenges, with an unacceptably high death toll
worldwide. In Morocco, medicinal plants continue to play a pivotal therapeutic role despite …

Potential of synthetic and natural compounds as novel histone deacetylase inhibitors for the treatment of hematological malignancies

D Pal, K Raj, SS Nandi, S Sinha, A Mishra, A Mondal… - Cancers, 2023 - mdpi.com
Simple Summary Histone deacetylases (HDACs) are epigenetic regulators that influence
chromatin structure and gene transcription, but also the function of non-histone targets like …

[HTML][HTML] Natural bioactive compounds targeting DNA methyltransferase enzymes in cancer: mechanisms insights and efficiencies

T Aanniz, A Bouyahya, A Balahbib, K El Kadri… - Chemico-Biological …, 2024 - Elsevier
The regulation of gene expression is fundamental to health and life and is essentially carried
out at the promoter region of the DNA of each gene. Depending on the molecular context …