The human history has witnessed the rapid development of technologies such as high-
throughput sequencing and mass spectrometry that led to the concept of “omics” and …

Cancer has myriad effects on metabolism that include both rewiring of intracellular
metabolism to enable cancer cells to proliferate inappropriately and adapt to the tumor …

Tumour cells have exquisite flexibility in reprogramming their metabolism in order to support
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …

The chirality of small metabolic molecules is important in controlling physiological processes
and indicating the health status of humans. Abnormal enantiomeric ratios of chiral molecules …

Ensiling is a microbial-driven process used to preserve fresh forage in bio-refinery and
animal production. The biochemical changes that ensue during ensiling have aided the …

Metabolomics investigates global metabolic alterations associated with chemical, biological,
physiological, or pathological processes. These metabolic changes are measured with …

Phototherapy (including photothermal therapy, PTT; and photodynamic therapy, PDT) has
been widely used for cancer treatment, but conventional PTT/PDT show limited therapeutic …

Highlights•Metabolomics has become a widely applied tool in drug development.•
Metabolomics plays a key role for the identification of physiological response markers.• …

Multiple sclerosis (MS) is an immune-mediated disease of the central nervous system that
causes demyelination, axonal degeneration and astrogliosis, resulting in progressive …

The manufacturing of recombinant protein is traditionally undertaken in mammalian cell
culture. Today, speed, cost and safety are the primary considerations for process …