Applications and challenges of ultra-small particle size nanoparticles in tumor therapy

J Xu, M Song, Z Fang, L Zheng, X Huang… - Journal of Controlled …, 2023 - Elsevier
With the development of nanotechnology, nanomedicines are widely used in tumor therapy.
However, biological barriers in the delivery of nanoparticles still limit their application in …

Stimuli‐responsive nanoparticles for controlled drug delivery in synergistic cancer immunotherapy

J Zhang, Y Lin, Z Lin, Q Wei, J Qian, R Ruan… - Advanced …, 2022 - Wiley Online Library
Cancer immunotherapy has achieved promising clinical progress over the recent years for
its potential to treat metastatic tumors and inhibit their recurrences effectively. However, low …

Intercalation‐Activated Layered MoO3 Nanobelts as Biodegradable Nanozymes for Tumor‐Specific Photo‐Enhanced Catalytic Therapy

Z Zhou, Y Wang, F Peng, F Meng, J Zha… - Angewandte …, 2022 - Wiley Online Library
The existence of natural van der Waals gaps in layered materials allows them to be easily
intercalated with varying guest species, offering an appealing strategy to optimize their …

Dual active centers linked by a reversible electron station as a multifunctional nanozyme to induce synergetically enhanced cascade catalysis for tumor-specific …

Q Zhao, L Zheng, Y Gao, J Li, J Wei… - Journal of the …, 2023 - ACS Publications
Nanozymes have shown great promise in reactive oxygen species (ROS)-mediated tumor
therapy with mitigated side effects but are normally limited by the complex tumor …

Iron Oxide Nanoparticles as T1 Contrast Agents for Magnetic Resonance Imaging: Fundamentals, Challenges, Applications, and Prospectives

M Jeon, MV Halbert, ZR Stephen… - Advanced materials, 2021 - Wiley Online Library
Gadolinium‐based chelates are a mainstay of contrast agents for magnetic resonance
imaging (MRI) in the clinic. However, their toxicity elicits severe side effects and the Food …

Biomedical polymers: synthesis, properties, and applications

WH Chen, QW Chen, Q Chen, C Cui, S Duan… - Science China …, 2022 - Springer
Biomedical polymers have been extensively developed for promising applications in a lot of
biomedical fields, such as therapeutic medicine delivery, disease detection and diagnosis …

Stimuli‐responsive crosslinked nanomedicine for cancer treatment

X Xue, H Qu, Y Li - Exploration, 2022 - Wiley Online Library
Nanomedicines are attractive paradigms to deliver drugs, contrast agents,
immunomodulators, and gene editors for cancer therapy and diagnosis. However, the …

An Ultrasound Activated Vesicle of Janus Au‐MnO Nanoparticles for Promoted Tumor Penetration and Sono‐Chemodynamic Therapy of Orthotopic Liver Cancer

X Lin, S Liu, X Zhang, R Zhu, S Chen… - Angewandte …, 2020 - Wiley Online Library
Sonodynamic therapy (SDT) has the advantages of high penetration, non‐invasiveness, and
controllability, and it is suitable for deep‐seated tumors. However, there is still a lack of …

Activatable NIR fluorescence/MRI bimodal probes for in vivo imaging by enzyme-mediated fluorogenic reaction and self-assembly

R Yan, Y Hu, F Liu, S Wei, D Fang… - Journal of the …, 2019 - ACS Publications
Stimuli-responsive in situ self-assembly of small molecules to form nanostructures in living
subjects has produced promising tools for molecular imaging and tissue engineering …

Dual key co-activated nanoplatform for switchable MRI monitoring accurate ferroptosis-based synergistic therapy

R Yue, C Zhang, L Xu, Y Wang, G Guan, L Lei, X Zhang… - Chem, 2022 - cell.com
Ferroptosis is of great significance for disease treatment and drug design because of its
effective damage to drug-resistant cells. However, ferroptosis-based therapy presents …