Bipolar affective disorder is a common neuropsychiatric disorder. Although its
neurobiological underpinnings are incompletely understood, the dopamine hypothesis has …

The resurgence of interest in anhedonia within major depression has been fuelled by
clinical trials demonstrating its utility in predicting antidepressant response as well as recent …

New evidence of reward processing abnormalities in MDD, bipolar disorder and
schizophrenia has led to a greater understanding of the neural processes associated with …

Background Two objectives of the NIMH Research Domain Criteria (RDoC) initiative are to
identify (a) mechanisms that are common to multiple psychiatric disorders, and (b) …

Objective In this critical review, the authors appraise neuroimaging findings in bipolar
disorder in emotion-processing, emotion-regulation, and reward-processing neural circuitry …

Anhedonia is a key symptom of major depressive disorder (MDD) and comprises
behavioural deficits in three reward processing subtypes: reward liking, reward wanting, and …

Many neuroimaging studies have investigated reward processing dysfunction in major
depressive disorder. These studies have led to the common idea that major depressive …

The cognitive model of depression has significantly influenced the understanding of
distorted cognitive processes in major depression; however, this model's conception of …

Distinguishing depression in bipolar disorder (BD) from unipolar depression (UD) solely
based on clinical clues is difficult, which has led to the exploration of promising neural …

Motivational and hedonic impairments are core aspects of a variety of types of
psychopathology. These impairments cut across diagnostic categories and may be critical to …