Viruses are obligate intracellular parasites. Despite their dependence on host cells, viruses
are evolutionarily autonomous, with their own genomes and evolutionary trajectories locked …

Protein structure is key to understanding biological function. Structure comparison deciphers
deep phylogenies, providing insight into functional conservation and functional shifts during …

The last universal cellular ancestor (LUCA) is the most recent population of organisms from
which all cellular life on Earth descends. The reconstruction of the genome and phenotype …

Structural comparison reveals remote homology that often fails to be detected by sequence
comparison. The DALI web server (http://ekhidna2. biocenter. helsinki. fi/dali) is a platform …

Enzymatic deconstruction of poly (ethylene terephthalate)(PET) is under intense
investigation, given the ability of hydrolase enzymes to depolymerize PET to its constituent …

De novo formation of the double-membrane compartment autophagosome is seeded by
small vesicles carrying membrane protein autophagy-related 9 (ATG9), the function of which …

Abstract Cyclic GMP–AMP synthase (cGAS) is a cytosolic DNA sensor that produces the
second messenger cG [2′–5′] pA [3′–5′] p (2′ 3′-cGAMP) and controls activation of …

Auxins are hormones that have central roles and control nearly all aspects of growth and
development in plants,–. The proteins in the PIN-FORMED (PIN) family (also known as the …

Bacterial conjugation is the fundamental process of unidirectional transfer of DNAs, often
plasmid DNAs, from a donor cell to a recipient cell. It is the primary means by which …

Membrane-sculpting proteins shape the morphology of cell membranes and facilitate
remodeling in response to physiological and environmental cues. Complexes of the …