Terminalia bellirica (Gaertn) Roxb. and Terminalia chebula Retz. are significant botanicals
in ancient Ayurvedic medicine. They are renowned for their therapeutic properties, notably in …

Background: Retrogenesis is the process by which the degenerative and vascular
mechanisms of dementias reverse the order of acquisition in the normal development …

Pediatric brain cancers, including gliomas and medulloblastomas, remain among the most
challenging malignancies to treat, with limited therapeutic options and poor survival …

The therapeutic potential of disrupting protein-protein interactions (PPIs) has emerged as a
promising strategy in cancer treatment, with a focus on sensitizing tumors to existing …

Phytochemicals have emerged as promising modulators of DNA repair pathways, offering
potential for targeted cancer therapies. This study focuses on pentagalloylglucose (PGG), a …

Integrating PARP inhibitors with radiotherapy represents a promising dual approach to
target DNA repair pathways in tumors, especially those with defective homologous …

Radiotherapy remains a cornerstone of cancer treatment, yet its efficacy is often limited by
tumor resistance due to efficient DNA repair mechanisms. Enhancing radiosensitivity in …

Pediatric brain tumors often exhibit unique genetic and epigenetic landscapes, with many
harboring DNA repair defects that make them susceptible to synthetic lethality strategies …