Novel advanced hydrogels can provide a versatile platform for controlled delivery and
release of various cargos, with a myriad of biomedical applications. These gel‐based …

Due to limitations of treatment and the stubbornness of infiltrative tumor cells, the outcome of
conventional antitumor treatment is often compromised by a variety of factors, including …

Bioorthogonal catalysis via transition metal catalysts (TMCs) enables the generation of
therapeutics locally through chemical reactions not accessible by biological systems. This …

After an osteosarcoma excision, recurrence and bone defects are significant challenges for
clinicians. In this study, the curcumin (Cur) loaded chitosan (CS) nanoparticles (CCNP) …

Non-specific toxicity of chemotherapeutics and evolution of malignant tumors against them
are major challenges for existing cancer chemotherapeutic regimens. Engineering of …

Fungal infections cause severe and life-threatening complications especially in
immunocompromised individuals. Antifungals targeting cellular machinery and cell …

Cancer immunotherapy can boost the immune response of patients to eliminate tumor cells
and suppress tumor metastasis and recurrence. However, immunotherapy resistance and …

Treatment of triple-negative breast cancer (TNBC) is challenging because of its “COLD”
tumor immunosuppressive microenvironment (TIME). Here, we present a hydrogel-mediated …

Sphingomyelin (SM) and its metabolites are crucial regulators of tumor cell growth,
differentiation, senescence, and programmed cell death. With the rise in lipid-based …

Simple Summary Existing chemotherapy treatments for breast cancer patients are high on
toxicity. There are very limited options available for triple-positive breast cancer (TPBC) …