Traumatic brain injury (TBI) is a serious disease that threatens life and health of people. It
poses a great economic burden on the healthcare system. Thus, seeking effective therapy to …

Perinatal hypoxic-ischemic encephalopathy (HIE) remains a major cause of morbidity and
mortality. Moderate hypothermia (33.5° C) is currently the sole established standard …

Hypoxic ischemic encephalopathy (HIE) is a serious birth complication affecting full-term
infants; 40% to 60% of affected infants die by 2 years old or have severe disabilities. Most …

Background In the last two decades, there has been considerable evolution in
understanding the role of erythropoietin in neuroprotection. Erythropoietin has both …

purpose. Erythropoietin (EPO), an oxygen-regulated hormone stimulating erythrocyte
production, was recently found to be critical for retinal angiogenesis. EPO mRNA expression …

Besides its established function in erythropoiesis, erythropoietin (EPO) is currently also
appreciated for its neuroprotective effects. The detrimental sequelae of prolonged cerebral …

OBJECTIVE. Erythropoietin has been shown to be protective against hypoxic-ischemic and
inflammatory injuries in cell culture, animal models of brain injury, and clinical trials of adult …

Neonatal stroke leads to mortality and severe morbidity, but there currently is no effective
treatment. Erythropoietin (EPO) promotes cytoprotection and neurogenesis in the short term …

Brain damage related to perinatal asphyxia is the second cause of neuro-disability
worldwide. Its incidence was estimated in 2010 as 8.5 cases per 1000 live births worldwide …

Neonatal brain injury, caused by perinatal hypoxia-ischemia and extreme prematurity,
remains a great challenge for prevention and treatment. There is no effective treatment for …