Exploiting non-covalent π interactions for catalyst design
Molecular recognition, binding and catalysis are often mediated by non-covalent interactions
involving aromatic functional groups. Although the relative complexity of these so-called π …
involving aromatic functional groups. Although the relative complexity of these so-called π …
Engineering hydrogel adhesion for biomedical applications via chemical design of the junction
Hydrogel adhesion inherently relies on engineering the contact surface at soft and hydrated
interfaces. Upon contact, adhesion normally occurs through the formation of chemical or …
interfaces. Upon contact, adhesion normally occurs through the formation of chemical or …
The realm of unconventional noncovalent interactions in proteins: their significance in structure and function
Electrons can tunnel through proteins in microseconds with a modest release of free energy
over distances in the 15 to 20 Å range. To span greater distances, or to move faster, multiple …
over distances in the 15 to 20 Å range. To span greater distances, or to move faster, multiple …
Structure and dynamics of the essential endogenous mycobacterial polyketide synthase Pks13
The mycolic acid layer of the Mycobacterium tuberculosis cell wall is essential for viability
and virulence, and the enzymes responsible for its synthesis are targets for …
and virulence, and the enzymes responsible for its synthesis are targets for …