The impact of the Fungus-Host-Microbiota interplay upon Candida albicans infections: current knowledge and new perspectives

C d'Enfert, AK Kaune, LR Alaban… - FEMS microbiology …, 2021 - academic.oup.com
Candida albicans is a major fungal pathogen of humans. It exists as a commensal in the oral
cavity, gut or genital tract of most individuals, constrained by the local microbiota, epithelial …

The regulation of hyphae growth in Candida albicans

H Chen, X Zhou, B Ren, L Cheng - Virulence, 2020 - Taylor & Francis
In the last decades, Candida albicans has served as the leading causal agent of life-
threatening invasive infections with mortality rates approaching 40% despite treatment …

Growth of Candida albicans hyphae

PE Sudbery - Nature Reviews Microbiology, 2011 - nature.com
The fungus Candida albicans is often a benign member of the mucosal flora; however, it
commonly causes mucosal disease with substantial morbidity and in vulnerable patients it …

The distinct morphogenic states of Candida albicans

P Sudbery, N Gow, J Berman - Trends in microbiology, 2004 - cell.com
The human fungal pathogen, Candida albicans can grow in at least three different
morphologies: yeast, pseudohyphae and hyphae. Further morphological forms exist during …

Regulatory circuitry governing fungal development, drug resistance, and disease

RS Shapiro, N Robbins, LE Cowen - Microbiology and molecular …, 2011 - journals.asm.org
Pathogenic fungi have become a leading cause of human mortality due to the increasing
frequency of fungal infections in immunocompromised populations and the limited …

Candida albicans: A molecular revolution built on lessons from budding yeast

J Berman, PE Sudbery - Nature Reviews Genetics, 2002 - nature.com
Candida albicans is an opportunistic fungal pathogen that is found in the normal
gastrointestinal flora of most healthy humans. However, in immunocompromised patients …

Coevolution of morphology and virulence in Candida species

DS Thompson, PL Carlisle, D Kadosh - Eukaryotic cell, 2011 - journals.asm.org
Many of the major human fungal pathogens are known to undergo morphological changes,
which in certain cases are associated with virulence. Although there has been an intense …

On Commensalism of Candida

JA Romo, CA Kumamoto - Journal of Fungi, 2020 - mdpi.com
Candida species are both opportunistic fungal pathogens and common members of the
human mycobiome. Over the years, the main focus of the fungal field has been on …

Systemic fungal infections caused by Candida species: epidemiology, infection process and virulence attributes

AL Mavor, S Thewes, B Hube - Current drug targets, 2005 - ingentaconnect.com
Candida species, in particular C. albicans, represent a major threat to immunocompromised
patients. Able to exist as a commensal on mucosal surfaces of healthy individuals, these …

Tip growth in filamentous fungi: a road trip to the apex

M Riquelme - Annual review of microbiology, 2013 - annualreviews.org
Fungal hyphae extend by apical growth. This process involves the polarized traffic of
secretory vesicles to the Spitzenkörper (SPK) and their subsequent distribution to specific …