Systems level studies of mammalian metabolomes: the roles of mass spectrometry and nuclear magnetic resonance spectroscopy

WB Dunn, DI Broadhurst, HJ Atherton… - Chemical society …, 2011 - pubs.rsc.org
The study of biological systems in a holistic manner (systems biology) is increasingly being
viewed as a necessity to provide qualitative and quantitative descriptions of the emergent …

Measuring the metabolome: current analytical technologies

WB Dunn, NJC Bailey, HE Johnson - Analyst, 2005 - pubs.rsc.org
The post-genomics era has brought with it ever increasing demands to observe and
characterise variation within biological systems. This variation has been studied at the …

[BOOK][B] Handbook of food science, technology, and engineering

YH Hui - 2006 - books.google.com
Handbook of food science, technology, and engineering Page 1 HANDBOOK of FOOD
SCIENCE, TECHNOLOGY, AND ENGINEERING Volume 4 Edited by YH HUI Associate Editors …

[BOOK][B] Olive oil: chemistry and technology

D Boskou - 2006 - taylorfrancis.com
A staple food for thousands of years in the Mediterranean region, olive oil is now becoming
popular all over the world. Olive oil has several unique characteristics that set it apart from …

Chemical derivatization and mass spectral libraries in metabolic profiling by GC/MS and LC/MS/MS

JM Halket, D Waterman… - Journal of …, 2005 - academic.oup.com
An overview is presented of gas chromatography/mass spectrometry (GC/MS) and liquid
chromatography/mass spectrometry (LC/MS), the two major hyphenated techniques …

Mass spectrometry in metabolome analysis

SG Villas‐Bôas, S Mas, M Åkesson… - Mass spectrometry …, 2005 - Wiley Online Library
In the post‐genomic era, increasing efforts have been made to describe the relationship
between the genome and the phenotype in cells and organisms. It has become clear that …

Fingerprinting food: current technologies for the detection of food adulteration and contamination

DI Ellis, VL Brewster, WB Dunn, JW Allwood… - Chemical Society …, 2012 - pubs.rsc.org
Major food adulteration and contamination events seem to occur with some regularity, such
as the widely publicised adulteration of milk products with melamine and the recent …

New advances in separation science for metabolomics: resolving chemical diversity in a post-genomic era

NL Kuehnbaum, P Britz-McKibbin - Chemical reviews, 2013 - ACS Publications
Metabolomics offers a revolutionary framework for phenoty** individuals at a molecular
level that is needed for new breakthroughs in cell biology and personalized medicine. 1− 3 …

High-throughput classification of yeast mutants for functional genomics using metabolic footprinting

J Allen, HM Davey, D Broadhurst, JK Heald… - Nature …, 2003 - nature.com
Many technologies have been developed to help explain the function of genes discovered
by systematic genome sequencing. At present, transcriptome and proteome studies …

Metabolomics and systems biology: making sense of the soup

DB Kell - Current opinion in microbiology, 2004 - Elsevier
Novel techniques for acquiring metabolomics data continue to emerge. Such data require
proper storage in suitably configured databases, which then permit one to establish the size …