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Strategies for heterologous expression, synthesis, and purification of animal venom toxins
Animal venoms are complex mixtures containing peptides and proteins known as toxins,
which are responsible for the deleterious effect of envenomations. Across the animal …
which are responsible for the deleterious effect of envenomations. Across the animal …
[HTML][HTML] Panorama of the intracellular molecular concert orchestrated by actinoporins, pore-forming toxins from sea anemones
Actinoporins (APs) are soluble pore-forming proteins secreted by sea anemones that
experience conformational changes originating in pores in the membranes that can lead to …
experience conformational changes originating in pores in the membranes that can lead to …
Decoupling immunomodulatory properties from lipid binding in the α-pore-forming toxin Sticholysin II
AL Rivero-Hernández, YP Hervis… - International Journal of …, 2024 - Elsevier
Sticholysin II (StII), a pore-forming toxin from the marine anemone Stichodactyla helianthus,
enhances an antigen-specific cytotoxic T lymphocyte (CTL) response when co-encapsulated …
enhances an antigen-specific cytotoxic T lymphocyte (CTL) response when co-encapsulated …
[HTML][HTML] Development of a StIW111C-based bioresponsive pore-forming conjugate for permeabilizing the endosomal membrane
FA Escalona-Rodriguez, J La O-Bonet… - International Journal of …, 2025 - Elsevier
Gene expression manipulation is pivotal in therapeutic approaches for various diseases.
Non-viral delivery systems present a safer alternative to viral vectors, with reduced …
Non-viral delivery systems present a safer alternative to viral vectors, with reduced …
Unveiling Sticholysin II and plasmid DNA interaction: Implications for develo** non-viral vectors
Non-viral gene delivery systems offer significant potential for gene therapy due to their
versatility, safety, and cost advantages over viral vectors. However, their effectiveness can …
versatility, safety, and cost advantages over viral vectors. However, their effectiveness can …
[HTML][HTML] Sea anemones, actinoporins, and cholesterol
J Palacios-Ortega, D Heras-Márquez… - International Journal of …, 2022 - mdpi.com
Spanish or Spanish-speaking scientists represent a remarkably populated group within the
scientific community studying pore-forming proteins. Some of these scientists, ourselves …
scientific community studying pore-forming proteins. Some of these scientists, ourselves …
Neurotoxins and pore forming toxins in sea anemones: Potential candidates for new drug development
ZL Wang, SY Zhang, SL Hao, WX Yang - 2023 - digitum.um.es
There are two kinds of toxins in sea anemones: neurotoxins and pore forming toxins. As a
representative of the sodium channel toxin, the neurotoxin ATX II in neurotoxin mainly affects …
representative of the sodium channel toxin, the neurotoxin ATX II in neurotoxin mainly affects …
Impact of intrinsic and extrinsic factors on cellular sphingomyelin imaging with specific reporter proteins
Sphingomyelin (SM) is a major sphingolipid in mammalian cells. Although SM is enriched in
the outer leaflet of the cell plasma membrane, lipids are also observed in the inner leaflet of …
the outer leaflet of the cell plasma membrane, lipids are also observed in the inner leaflet of …
Recombinant production in Escherichia coli of functionally active alpha-hemolysin from the human pathogen Staphylococcus aureus
JL Diaz-Varela, V Sabia, D Heras-Marquez… - bioRxiv, 2025 - biorxiv.org
Staphylococcus aureus is a human opportunistic pathogen capable of causing multiple
infections in both humans and animals. It secretes a group of exotoxins, known as …
infections in both humans and animals. It secretes a group of exotoxins, known as …
[PDF][PDF] Coelenterate toxins, its pharmaceutical and therapeutic effects
S SHARMA, RK UPADHYAY - Int J Curr Pharm Res, 2021 - academia.edu
Present review article emphasizes species specific coelenterate toxins, its pharmaceutical
and therapeutic effects. Most of the coelenterates inflict venom accidently by using …
and therapeutic effects. Most of the coelenterates inflict venom accidently by using …