Rigidity transitions in development and disease

E Hannezo, CP Heisenberg - Trends in Cell Biology, 2022 - cell.com
Although rigidity and jamming transitions have been widely studied in physics and material
science, their importance in a number of biological processes, including embryo …

Accessing activity and viscoelastic properties of artificial and living systems from passive measurement

TM Muenker, G Knotz, M Krüger, T Betz - Nature Materials, 2024 - nature.com
Living systems are complex dynamic entities that operate far from thermodynamic
equilibrium. Their active, non-equilibrium behaviour requires energy to drive cellular …

Dissecting flux balances to measure energetic costs in cell biology: techniques and challenges

E Arunachalam, W Ireland, X Yang… - Annual Review of …, 2023 - annualreviews.org
Life is a nonequilibrium phenomenon: Metabolism provides a continuous supply of energy
that drives nearly all cellular processes. However, very little is known about how much …

Symmetry, thermodynamics, and topology in active matter

MJ Bowick, N Fakhri, MC Marchetti, S Ramaswamy - Physical Review X, 2022 - APS
The name active matter refers to any collection of entities that individually use free energy to
generate their own motion and forces. Through interactions, active particles spontaneously …

Irreversible mesoscale fluctuations herald the emergence of dynamical phases

T Suchanek, K Kroy, SAM Loos - Physical Review Letters, 2023 - APS
We study fluctuating field models with spontaneously emerging dynamical phases. We
consider two typical transition scenarios associated with parity-time symmetry breaking …

Time-reversal symmetry breaking in the chemosensory array reveals a general mechanism for dissipation-enhanced cooperative sensing

D Hathcock, Q Yu, Y Tu - Nature Communications, 2024 - nature.com
The Escherichia coli chemoreceptors form an extensive array that achieves cooperative and
adaptive sensing of extracellular signals. The receptors control the activity of histidine kinase …

Dissipation and energy propagation across scales in an active cytoskeletal material

PJ Foster, J Bae, B Lemma, J Zheng, W Ireland… - Proceedings of the …, 2023 - pnas.org
Living systems are intrinsically nonequilibrium: They use metabolically derived chemical
energy to power their emergent dynamics and self-organization. A crucial driver of these …

Thermodynamic limits of sperm swimming precision

C Maggi, F Saglimbeni, VC Sosa, R Di Leonardo… - PRX life, 2023 - APS
Sperm swimming is crucial to fertilize the egg, in nature and in assisted reproductive
technologies. Modeling the sperm dynamics involves elasticity, hydrodynamics, internal …

Universal bounds on entropy production inferred from observed statistics

E Nitzan, A Ghosal, G Bisker - Physical Review Research, 2023 - APS
Nonequilibrium processes break time-reversal symmetry and generate entropy. Living
systems are driven out-of-equilibrium at the microscopic level of molecular motors that …

Uncovering nonequilibrium from unresolved events

PE Harunari - Physical Review E, 2024 - APS
Closely related to the laws of thermodynamics, the detection and quantification of
disequilibria are crucial in unraveling the complexities of nature, particularly those beneath …