Direct and reverse pluronic micelles: Design and characterization of promising drug delivery nanosystems

A Naharros-Molinero, MÁ Caballo-González… - Pharmaceutics, 2022 - mdpi.com
Pluronics are a family of amphiphilic block copolymers broadly explored in the
pharmaceutical field. Under certain conditions, Pluronics self-assemble in different …

Novel Supramolecular Nanoparticles Modified with Phosphatidylcholine Improve the Bioavailability of Fisetin and Alleviate Alcoholism through Antioxidant and …

Q Ren, J Jiang, P Huang, X Liang, C He… - ACS Applied Nano …, 2024 - ACS Publications
Excessive alcohol consumption frequently induces pathological alterations in various
organs. Currently, there is no specific therapeutic drug for the treatment of alcoholism …

Amphiphilic micelles as superior nanocarriers in drug delivery: from current preclinical surveys to structural frameworks

FA Wani, K Behera, R Patel - ChemistrySelect, 2022 - Wiley Online Library
The designing of suitable carriers for the delivery of hydrophobic drugs is highly challenging
for researchers. Solubilization of drugs is of immense importance for drug development …

Improving properties of baricitinib due to interaction with Pluronic micelles

A Garibyan, E Delyagina, I Terekhova - Journal of Molecular Liquids, 2023 - Elsevier
Baricitinib is a new generation medicinal compound that has been recommended for the
treatment of rheumatoid arthritis in 2017 as well as alopecia areata and COVID-19 in 2022 …

Design, Development, and Evaluation of SA-F127:TPGS Polymeric Mixed Micelles for Improved Delivery of Glipizide Drug: In-vitro, Ex-vivo, and In-vivo …

HS Patel, BA Vyas, S Tripathi, RK Sharma - AAPS PharmSciTech, 2023 - Springer
The anti-diabetic glipizide (GLN) drug has notable pharmaceutical advantages, but poor
aqueous solubility restricts its wide applications. The present work was to develop a mixed …

Comparative Analysis of Bare and Quercetin-Loaded Nonionic Block Copolymer Micelles in an Artificial Gastrointestinal Medium

SV Bhandarkar, S Agrawal, RB Salunkhe, A Putta… - Langmuir, 2024 - ACS Publications
Block copolymer micelles have been increasingly used for the solubilization and delivery of
hydrophobic drugs. There exists a possibility of dissociation of micelles and formation of …

[HTML][HTML] Everolimus-encapsulation in Pluronic P123 self-assembled micelles as drug delivery systems for drug-coated balloons

M Akrami-Hasan-Kohal, A Chouchou… - International Journal of …, 2024 - Elsevier
Drug-coated balloons (DCBs) are effective tools for cardiovascular interventions, ensuring
uniform drug delivery to occluded arteries. This research investigates the potential of …

Pluronic-coated hydroxypropyl-β-cyclodextrin nanoparticle potentiated chemotherapy on multidrug resistance cancer cells via improved docetaxel loading and P …

JS Lee, H Jeon, H Oh, P Son, D Lee, SY Cheon… - Journal of Drug Delivery …, 2024 - Elsevier
In the pharmaceutical formulation of anticancer drugs, US FDA-approved cyclodextrin (CD)
and its derivates have been widely employed. Among them, hydroxypropyl β-cyclodextrin …

[HTML][HTML] Novel Oxygen-and Curcumin-Laden Ionic Liquid@ Silica Nanocapsules for Enhanced Antimicrobial Photodynamic Therapy

J Henriques, J Pina, MEM Braga, A Dias, P Coimbra… - Pharmaceutics, 2023 - mdpi.com
The efficiency of photodynamic therapy is often limited by the scarcity of oxygen at the target
site. To address this problem, this work proposes the development of a new nanosystem for …

Mixed Pluronic/lecithin micelles formulation for oral bioavailability of candesartan cilexetil drug: in vitro characterization and in vivo pharmacokinetic investigations

H Mahajan, HS Patel, D Ray, VK Aswal… - Drug Development …, 2024 - Taylor & Francis
Objective This study aimed to develop a mixed polymeric micelle formulation incorporating
candesartan cilexetil (CAND) drug to enhance its oral bioavailability for the better treatment …