Recent advances of PLGA micro/nanoparticles for the delivery of biomacromolecular therapeutics

D Ding, Q Zhu - Materials Science and Engineering: C, 2018 - Elsevier
Recent advancements in biopharmaceutical industry have facilitated the development of
novel bioactive macromolecular therapeutics. One of the challenges towards the clinical use …

PLGA-based nanoparticles: an overview of biomedical applications

F Danhier, E Ansorena, JM Silva, R Coco… - Journal of controlled …, 2012 - Elsevier
Poly (lactic-co-glycolic acid)(PLGA) is one of the most successfully developed
biodegradable polymers. Among the different polymers developed to formulate polymeric …

Surface modification and endothelialization of biomaterials as potential scaffolds for vascular tissue engineering applications

X Ren, Y Feng, J Guo, H Wang, Q Li, J Yang… - Chemical Society …, 2015 - pubs.rsc.org
Surface modification and endothelialization of vascular biomaterials are common
approaches that are used to both resist the nonspecific adhesion of proteins and improve …

Growth factor delivery: Defining the next generation platforms for tissue engineering

LMC Aguilar, SM Silva, SE Moulton - Journal of controlled Release, 2019 - Elsevier
Growth factors play a crucial role in tissue engineering by directing the fate of cells and
allowing the formation of tissues. Understanding the key requirements for growth factor …

[HTML][HTML] Vascular endothelial growth factor (VEGF) delivery approaches in regenerative medicine

N Beheshtizadeh, M Gharibshahian, M Bayati… - Biomedicine & …, 2023 - Elsevier
The utilization of growth factors in the process of tissue regeneration has garnered
significant interest and has been the subject of extensive research. However, despite the …

Oxygen and nutrient delivery in tissue engineering: Approaches to graft vascularization

T Rademakers, JM Horvath… - Journal of tissue …, 2019 - Wiley Online Library
The field of tissue engineering is making great strides in develo** replacement tissue
grafts for clinical use, marked by the rapid development of novel biomaterials, their improved …

Regeneration of skin appendages and nerves: current status and further challenges

T Weng, P Wu, W Zhang, Y Zheng, Q Li, R **… - Journal of translational …, 2020 - Springer
Abstract Tissue-engineered skin (TES), as an analogue of native skin, is promising for
wound repair and regeneration. However, a major drawback of TES products is a lack of …

3D bioprinting mesenchymal stem cell-laden construct with core–shell nanospheres for cartilage tissue engineering

W Zhu, H Cui, B Boualam, F Masood, E Flynn… - …, 2018 - iopscience.iop.org
Cartilage tissue is prone to degradation and has little capacity for self-healing due to its
avascularity. Tissue engineering, which provides artificial scaffolds to repair injured tissues …

PLGA nanoparticles loaded with host defense peptide LL37 promote wound healing

KK Chereddy, CH Her, M Comune, C Moia… - Journal of Controlled …, 2014 - Elsevier
Wound treatment remains one of the most prevalent and economically burdensome
healthcare issues in the world. Poly (lactic-co-glycolic acid)(PLGA) supplies lactate that …

Materials science and design principles of growth factor delivery systems in tissue engineering and regenerative medicine

R Subbiah, RE Guldberg - Advanced healthcare materials, 2019 - Wiley Online Library
Growth factors (GFs) are signaling molecules that direct cell development by providing
biochemical cues for stem cell proliferation, migration, and differentiation. GFs play a key …