Role of reactive oxygen species in aging and age-related diseases: A review

MI Anik, N Mahmud, AA Masud, MI Khan… - ACS Applied Bio …, 2022 - ACS Publications
Research on the role of reactive oxygen species (ROS) in the aging process has advanced
significantly over the last two decades. In light of recent findings, ROS takes part in the aging …

Moroccan antidiabetic medicinal plants: Ethnobotanical studies, phytochemical bioactive compounds, preclinical investigations, toxicological validations and clinical …

A Bouyahya, N El Omari, N Elmenyiy… - Trends in Food Science …, 2021 - Elsevier
Background Moroccan flora is rich with medicinal plants that are widely used in traditional
medicine for the treatment of various diseases including diabetes. These plants possess …

The human islet: mini-organ with mega-impact

JT Walker, DC Saunders, M Brissova… - Endocrine …, 2021 - academic.oup.com
This review focuses on the human pancreatic islet—including its structure, cell composition,
development, function, and dysfunction. After providing a historical timeline of key …

Phenolic bioactives from plant-based foods for glycemic control

D Sarkar, A Christopher, K Shetty - Frontiers in Endocrinology, 2022 - frontiersin.org
Plant-based foods containing phenolic bioactives have human health protective functions
relevant for combating diet and lifestyle-influenced chronic diseases, including type 2 …

HNF1A: From Monogenic Diabetes to Type 2 Diabetes and Gestational Diabetes Mellitus

LM Li, BG Jiang, LL Sun - Frontiers in Endocrinology, 2022 - frontiersin.org
Diabetes, a disease characterized by hyperglycemia, has a serious impact on the lives and
families of patients as well as on society. Diabetes is a group of highly heterogeneous …

Electrochemical sensors based on carbon nanomaterial used in diagnosing metabolic disease

C Zhang, X Du - Frontiers in Chemistry, 2020 - frontiersin.org
Metabolic diseases have become common diseases with the improvement of living
standards because of changed dietary habits and living habits, which seriously affect health …

Regulatory role of Apelin-13-mediated PI3K/AKT signaling pathway in the glucose and lipid metabolism of mouse with gestational diabetes mellitus

XD Zheng, Y Huang, H Li - Immunobiology, 2021 - Elsevier
Objective To investigate the regulatory mechanism of Apelin-13-mediated PI3K/AKT
signaling pathway in the glucose and lipid metabolism of gestational diabetes mellitus …

Saudi Community-Based Screening Study on Genetic Variants in β-Cell Dysfunction and Its Role in Women with Gestational Diabetes Mellitus

AF Alshammary, MM Al-Hakeem, I Ali Khan - Genes, 2023 - mdpi.com
Background: Diabetes (hyperglycemia) is defined as a multifactorial metabolic disorder in
which insulin resistance and defects in pancreatic β-cell dysfunction are two major …

Genomics and epigenomics of gestational diabetes mellitus: understanding the molecular pathways of the disease pathogenesis

N Abu Samra, HF Jelinek, H Alsafar, F Asghar… - International journal of …, 2022 - mdpi.com
One of the most common complications during pregnancy is gestational diabetes mellitus
(GDM), hyperglycemia that occurs for the first time during pregnancy. The condition is …

Epigenetic alternations of microRNAs and DNA methylation contribute to gestational diabetes mellitus

W Zhu, Y Shen, J Liu, X Fei, Z Zhang… - Journal of Cellular …, 2020 - Wiley Online Library
This study aimed to identify epigenetic alternations of microRNAs and DNA methylation for
gestational diabetes mellitus (GDM) diagnosis and treatment using in silico approach. Data …