[HTML][HTML] Targeting the tumor microenvironment: Potential strategy for cancer therapeutics
Cellular and stromal components including tumor cells, immune cells, mesenchymal cells,
cancer-linked fibroblasts, and extracellular matrix, constituent tumor microenvironment …
cancer-linked fibroblasts, and extracellular matrix, constituent tumor microenvironment …
Recent updates on thienopyrimidine derivatives as anticancer agents
Thienopyrimidine derivatives hold a unique place between fused pyrimidine compounds.
They are important and widely represented in medicinal chemistry as they are structural …
They are important and widely represented in medicinal chemistry as they are structural …
Development of new thieno [2, 3-d] pyrimidines as dual EGFR and STAT3 inhibitors endowed with anticancer and pro-apoptotic activities
In part due to the resilience of cellular feedback pathways that develop therapeutic
resistance to targeting the EGFR alone, using EGFR inhibitors alone was demonstrated to …
resistance to targeting the EGFR alone, using EGFR inhibitors alone was demonstrated to …
Design and efficient synthesis of new 4-amino-substituted 2-(4-Bromobenzyl)-5, 6, 7, 8-tetrahydrobenzo [4, 5] thieno [2, 3-d] pyrimidines of anticancer interest and their …
Thienopyrimidines are an emerging class of fused pyrimidines due to their broad spectrum
of pharmacological properties, including antimicrobial, anti-inflammatory, antimalarial …
of pharmacological properties, including antimicrobial, anti-inflammatory, antimalarial …