[HTML][HTML] Antibiotic resistance in microbes: History, mechanisms, therapeutic strategies and future prospects

TM Uddin, AJ Chakraborty, A Khusro… - Journal of infection and …, 2021 - Elsevier
Antibiotics have been used to cure bacterial infections for more than 70 years, and these low-
molecular-weight bioactive agents have also been used for a variety of other medicinal …

How antimicrobial resistance is linked to climate change: an overview of two intertwined global challenges

R Magnano San Lio, G Favara, A Maugeri… - International journal of …, 2023 - mdpi.com
Globally, antimicrobial resistance (AMR) and climate change (CC) are two of the top health
emergencies, and can be considered as two interlinked public health priorities. The complex …

Metagenomics-enabled microbial surveillance

KKK Ko, KR Chng, N Nagarajan - Nature Microbiology, 2022 - nature.com
Lessons learnt from the COVID-19 pandemic include increased awareness of the potential
for zoonoses and emerging infectious diseases that can adversely affect human health …

Toward a universal unit for quantification of antibiotic resistance genes in environmental samples

X Yin, X Chen, XT Jiang, Y Yang, B Li… - Environmental …, 2023 - ACS Publications
Surveillance of antibiotic resistance genes (ARGs) has been increasingly conducted in
environmental sectors to complement the surveys in human and animal sectors under the …

Antibiotic resistome from the One-Health perspective: understanding and controlling antimicrobial resistance transmission

DW Kim, CJ Cha - Experimental & molecular medicine, 2021 - nature.com
The concept of the antibiotic resistome was introduced just over a decade ago, and since
then, active resistome studies have been conducted. In the present study, we describe the …

Role played by the environment in the emergence and spread of antimicrobial resistance (AMR) through the food chain

EFSA Panel on Biological Hazards (BIOHAZ)… - Efsa …, 2021 - Wiley Online Library
The role of food‐producing environments in the emergence and spread of antimicrobial
resistance (AMR) in EU plant‐based food production, terrestrial animals (poultry, cattle and …

Global monitoring of antimicrobial resistance based on metagenomics analyses of urban sewage

RS Hendriksen, P Munk, P Njage, B Van Bunnik… - Nature …, 2019 - nature.com
Antimicrobial resistance (AMR) is a serious threat to global public health, but obtaining
representative data on AMR for healthy human populations is difficult. Here, we use …

Epidemic of carbapenem-resistant Klebsiella pneumoniae in Europe is driven by nosocomial spread

S David, S Reuter, SR Harris, C Glasner, T Feltwell… - Nature …, 2019 - nature.com
Public health interventions to control the current epidemic of carbapenem-resistant
Klebsiella pneumoniae rely on a comprehensive understanding of its emergence and …

Sequencing-based methods and resources to study antimicrobial resistance

M Boolchandani, AW D'Souza, G Dantas - Nature Reviews Genetics, 2019 - nature.com
Antimicrobial resistance extracts high morbidity, mortality and economic costs yearly by
rendering bacteria immune to antibiotics. Identifying and understanding antimicrobial …

Using genomics to track global antimicrobial resistance

RS Hendriksen, V Bortolaia, H Tate, GH Tyson… - Frontiers in public …, 2019 - frontiersin.org
The recent advancements in rapid and affordable DNA sequencing technologies have
revolutionized diagnostic microbiology and microbial surveillance. The availability of …