Biosynthesis of monoterpenoid and sesquiterpenoid as natural flavors and fragrances

H Jiang, X Wang - Biotechnology Advances, 2023 - Elsevier
Terpenoids are a large class of plant-derived compounds, that constitute the main
components of essential oils and are widely used as natural flavors and fragrances. The …

Formation of starch in plant cells

B Pfister, SC Zeeman - Cellular and molecular life sciences, 2016 - Springer
Starch-rich crops form the basis of our nutrition, but plants have still to yield all their secrets
as to how they make this vital substance. Great progress has been made by studying both …

Complete biosynthesis of cannabinoids and their unnatural analogues in yeast

X Luo, MA Reiter, L d'Espaux, J Wong, CM Denby… - Nature, 2019 - nature.com
Cannabis sativa L. has been cultivated and used around the globe for its medicinal
properties for millennia. Some cannabinoids, the hallmark constituents of Cannabis, and …

A chloroplast protein atlas reveals punctate structures and spatial organization of biosynthetic pathways

L Wang, W Patena, KA Van Baalen, Y **e, ER Singer… - Cell, 2023 - cell.com
Chloroplasts are eukaryotic photosynthetic organelles that drive the global carbon cycle.
Despite their importance, our understanding of their protein composition, function, and …

LOCALIZER: subcellular localization prediction of both plant and effector proteins in the plant cell

J Sperschneider, AM Catanzariti, K DeBoer, B Petre… - Scientific reports, 2017 - nature.com
Pathogens secrete effector proteins and many operate inside plant cells to enable infection.
Some effectors have been found to enter subcellular compartments by mimicking host …

Green diatom mutants reveal an intricate biosynthetic pathway of fucoxanthin

Y Bai, T Cao, O Dautermann, P Buschbeck… - Proceedings of the …, 2022 - pnas.org
Fucoxanthin is a major light-harvesting pigment in ecologically important algae such as
diatoms, haptophytes, and brown algae (Phaeophyceae). Therefore, it is a major driver of …

Metabolic engineering of Escherichia coli with electron channelling for the production of natural products

SY Park, H Eun, MH Lee, SY Lee - Nature Catalysis, 2022 - nature.com
The biosynthesis of natural products often requires eukaryotic cytochrome P450s (P450s) in
combination with P450 reductase, in physical proximity, to perform electron-transfer …

Industrial brewing yeast engineered for the production of primary flavor determinants in hopped beer

CM Denby, RA Li, VT Vu, Z Costello, W Lin… - Nature …, 2018 - nature.com
Flowers of the hop plant provide both bitterness and “hoppy” flavor to beer. Hops are,
however, both a water and energy intensive crop and vary considerably in essential oil …

Predicting subcellular localization of proteins based on their N-terminal amino acid sequence

O Emanuelsson, H Nielsen, S Brunak… - Journal of molecular …, 2000 - Elsevier
A neural network-based tool, TargetP, for large-scale subcellular location prediction of newly
identified proteins has been developed. Using N-terminal sequence information only, it …

Locating proteins in the cell using TargetP, SignalP and related tools

O Emanuelsson, S Brunak, G Von Heijne, H Nielsen - Nature protocols, 2007 - nature.com
Determining the subcellular localization of a protein is an important first step toward
understanding its function. Here, we describe the properties of three well-known N-terminal …