Define chronic post-surgical pain (CPSP) according to the ICD-11 (International
Classification of Diseases, Eleventh Revision) classification and describe its impact on …

Opioids are the most potent of all analgesics. Although traditionally used solely for acute self-
limited conditions and palliation of severe cancer-associated pain, a movement to promote …

Objective: Evaluate the association between postoperative opioid prescribing and new
persistent opioid use. Summary Background Data: Opioid-nave patients who develop new …

This paper is the forty-fifth consecutive installment of the annual anthological review of
research concerning the endogenous opioid system, summarizing articles published during …

The statements and recommendations contained in this report are primarily based on the
available literature and expert consensus. Decisions should be individualized and tailored …

Background: A significant amount of evidence suggests that Opioid-Free Anaesthesia (OFA)
may provide better outcomes for patients undergoing surgery, sparing patients who are …

Persistent postoperative pain (PPP) after cardiac surgery is a significant complication that
negatively affects patient quality of life and increases health care system burden. However …

Background Opioid-based anesthesia and analgesia is a traditional component of
perioperative care for the cardiac surgery patient. Growing enthusiasm for Enhanced …

Background The epidemiology of persistent postoperative opioid use at least 3 months after
cardiac surgery is poorly characterised despite its potential public health importance …

Abstract Purpose of Review This review aims to summarize interventions used in the
perioperative period to reduce the development of new persistent postoperative opioid use …