Metal–organic frameworks for biological applications

I Abánades Lázaro, X Chen, M Ding… - Nature Reviews …, 2024 - nature.com
Metal–organic frameworks (MOFs) have emerged as exciting potential new candidates for
application across nanomedicine, with the first example now in a phase II human clinical …

The promise and potential of metal–organic frameworks and covalent organic frameworks in vaccine nanotechnology

YH Wijesundara, TS Howlett, S Kumari… - Chemical …, 2024 - ACS Publications
The immune system's complexity and ongoing evolutionary struggle against deleterious
pathogens underscore the value of vaccination technologies, which have been bolstering …

Clinical translation of metal–organic frameworks

N Tyagi, YH Wijesundara, JJ Gassensmith… - Nature Reviews …, 2023 - nature.com
Clinical translation of metal–organic frameworks | Nature Reviews Materials Skip to main
content Thank you for visiting nature.com. You are using a browser version with limited support …

[HTML][HTML] Biomimetic functionalized metal organic frameworks as multifunctional agents: paving the way for cancer vaccine advances

B Tousian, AR Khosravi, MH Ghasemi… - Materials Today Bio, 2024 - Elsevier
Vaccination is poised to be a highly effective immunotherapy approach for numerous
illnesses in the forthcoming years. Considerable attention has been given to the …

Rational Design of Metal–Organic Frameworks for Pancreatic Cancer Therapy: from Machine Learning Screening to In Vivo Efficacy

F Melle, D Menon, J Conniot… - Advanced …, 2025 - Wiley Online Library
Despite improvements in cancer survival rates, metastatic and surgery‐resistant cancers,
such as pancreatic cancer, remain challenging, with poor prognoses and limited treatment …

Nanoengineering of vaccine nanoparticles via templating of metal–organic frameworks for tumor immunotherapy

Y Liu, N Wang, M Li, Z Gao, G Zhang, Y Yang… - Chemistry of …, 2024 - ACS Publications
We present a facile strategy to fabricate nanovaccines through a metal–organic framework-
templated method. The nanovaccines, named IMDQ@ OVA-TA, were obtained through the …

A Self‐Adjuvanting Large Pore 2D Covalent Organic Framework as a Vaccine Platform

YH Wijesundara, N Arora, RN Ehrman… - Angewandte …, 2025 - Wiley Online Library
Vaccines are one of the greatest human achievements in public health, as they help prevent
the spread of diseases, reduce illness and death rates, saving thousands of lives with few …

Improving the colloidal stability of protein@ ZIF-8 nanoparticles in biologically relevant buffers

J Van Houten, RC Barberi, J King, AF Ogata - Materials Advances, 2024 - pubs.rsc.org
ZIF-8 is one of the most common metal–organic frameworks used in protein encapsulation
and is advantageous for the protection of protein function and delivery of protein cargo …

Testing the Antigenic Potential of Transmembrane Proteins To Develop a Thermostable Tuberculosis MOF-Liposomal Vaccine

S Kumari, J Martinez-Garcia, RN Ehrman… - ACS infectious …, 2024 - ACS Publications
Tuberculosis is one of the deadliest infectious diseases and continues to be a major health
risk in many parts of the world. Even today, the century-old Bacillus Calmette-Guerin (BCG) …

Dually functionalized dendrimer for stimuli-responsive release of active ingredients into the skin

O Trashi, N Satish, I Trashi, LM Hagge… - Acta Biomaterialia, 2025 - Elsevier
The skin, our largest organ, protects against environmental dangers but is vulnerable to
various conditions like infections, eczema, dermatitis, psoriasis, skin cancer, and age-related …