Obesity is causally linked with the development of cardiovascular disorders. Accumulating
evidence indicates that cardiovascular disease is the collateral damage of obesity-driven …

There are three dominant contributors to the pathogenesis of dysfunctional adipose tissue
(AT) in obesity: unresolved inflammation, inappropriate extracellular matrix (ECM) …

While most tissues exhibit their greatest growth during development, adipose tissue is
capable of additional massive expansion in adults. Adipose tissue expandability is …

Obesity and the metabolic syndrome (MS) are two of the pressing healthcare problems of
our time. The MS is defined as increased abdominal obesity in concert with elevated fasting …

The prevalence of obesity is increasing and progressively influencing physician‐patient
interactions. While there is a sizable amount of data demonstrating that obesity is a state of …

Obesity is a risk factor for various cardiovascular diseases including hypertension,
atherosclerosis, and myocardial infarction. Recent studies aimed at understanding the …

To fulfill its role as the major energy-storing tissue, adipose has several unique properties
that cannot be seen in any other organ, including an almost unlimited capacity to expand in …

The obesity epidemic has led researchers and clinicians to reconsider the etiology of this
disease and precisely decipher its molecular mechanisms. The excessive accumulation of …

Inflammation is increasingly regarded as a key process underlying metabolic diseases in
obese individuals. In particular, obese adipose tissue shows features characteristic of active …

Metabolic disorders, such as obesity, type 2 diabetes mellitus, and nonalcoholic fatty liver
disease, are characterized by chronic low-grade tissue and systemic inflammation. During …