[HTML][HTML] Stem cells derived exosomes and biomaterials to modulate autophagy and mend broken hearts
N Sareen, A Srivastava, KN Alagarsamy… - … et Biophysica Acta (BBA …, 2023 - Elsevier
Autophagy maintains cellular homeostasis and plays a crucial role in managing pathological
conditions including ischemic myocardial injury leading to heart failure (HF). Despite …
conditions including ischemic myocardial injury leading to heart failure (HF). Despite …
Toward cardiac regeneration: combination of pluripotent stem cell-based therapies and bioengineering strategies
M Mazzola, E Di Pasquale - Frontiers in Bioengineering and …, 2020 - frontiersin.org
Cardiovascular diseases represent the major cause of morbidity and mortality worldwide.
Multiple studies have been conducted so far in order to develop treatments able to prevent …
Multiple studies have been conducted so far in order to develop treatments able to prevent …
ROS-responsive polyurethane fibrous patches loaded with methylprednisolone (MP) for restoring structures and functions of infarcted myocardium in vivo
Y Yao, J Ding, Z Wang, H Zhang, J **e, Y Wang… - Biomaterials, 2020 - Elsevier
Reactive oxygen species (ROS) play an important role in the pathogenesis of numerous
diseases including atherosclerosis, diabetes, inflammation and myocardial infarction (MI). In …
diseases including atherosclerosis, diabetes, inflammation and myocardial infarction (MI). In …
[HTML][HTML] Natural myocardial ECM patch drives cardiac progenitor based restoration even after scarring
U Sarig, H Sarig, E de-Berardinis, SY Chaw… - Acta biomaterialia, 2016 - Elsevier
Objective To evaluate the regenerative capacity of non-supplemented and bioactive patches
made of decellularized porcine cardiac extracellular matrix (pcECM) and characterize the …
made of decellularized porcine cardiac extracellular matrix (pcECM) and characterize the …
Injectable hyaluronic acid based microrods provide local micromechanical and biochemical cues to attenuate cardiac fibrosis after myocardial infarction
LV Le, P Mohindra, Q Fang, RE Sievers, MA Mkrtschjan… - Biomaterials, 2018 - Elsevier
Repairing cardiac tissue after myocardial infarction (MI) is one of the most challenging goals
in tissue engineering. Following ischemic injury, significant matrix remodeling and the …
in tissue engineering. Following ischemic injury, significant matrix remodeling and the …
Three‐dimensional collagenous niche and azacytidine selectively promote time‐dependent cardiomyogenesis from human bone marrow‐derived MSC spheroids
Endogenous adult cardiac regenerative machinery is not capable of replacing the lost cells
following myocardial infarction, often leading to permanent alterations in structure‐function …
following myocardial infarction, often leading to permanent alterations in structure‐function …
Myocardial infarction from a tissue engineering and regenerative medicine point of view: A comprehensive review on models and treatments
In the modern world, myocardial infarction is one of the most common cardiovascular
diseases, which are responsible for around 18 million deaths every year or almost 32% of all …
diseases, which are responsible for around 18 million deaths every year or almost 32% of all …
Engineering functional cardiac tissues for regenerative medicine applications
Abstract Purpose of Review Tissue engineering has expanded into a highly versatile
manufacturing landscape that holds great promise for advancing cardiovascular …
manufacturing landscape that holds great promise for advancing cardiovascular …
Strategies and challenges to myocardial replacement therapy
NT Feric, M Radisic - Stem cells translational medicine, 2016 - academic.oup.com
Cardiovascular diseases account for the majority of deaths globally and are a significant
drain on economic resources. Although heart transplants and left-ventricle assist devices are …
drain on economic resources. Although heart transplants and left-ventricle assist devices are …
Poly (lactic acid) as biomaterial for cardiovascular devices and tissue engineering applications
W Hadasha, D Bezuidenhout - Industrial Applications of Poly (lactic acid), 2018 - Springer
Synthetic bioabsorbable polymers, such as poly-lactic acid (PLA) and its copolymers (PLA-
based polymers), have attracted a lot of attention in the medical field. With their excellent …
based polymers), have attracted a lot of attention in the medical field. With their excellent …