Uterine leiomyomas, also known as uterine fibroids, are the most common pelvic tumors,
occurring in nearly 70% of all reproductive-aged women and are the leading indication for …

Background: The occurrence and progression of cancer are the results of the dysregulation
of genetics and epigenetics. Epigenetic regulation can reversibly affect gene transcription …

The histone deacetylase inhibitor (HDACi) LBH589 has been verified as an effective
anticancer agent. The identification and characterization of new targets for LBH589 action …

Uterine leiomyomas, also called uterine fibroids or myomas, represent one of the most
common benign tumour types in women of a fertile age. Leiomyomas arise due to …

Death-associated protein kinase 1 (DAPK) is an important serine/threonine kinase involved
in various cellular processes, including apoptosis, autophagy, and inflammation. DAPK …

The activation of AKT governs many signaling pathways and promotes cell growth and
inhibits apoptosis in human malignancies including prostate cancer (CaP). Here, we …

Utilization of liquid biopsy in the management of cancerous diseases is becoming more
attractive. This method can overcome typical limitations of tissue biopsies, especially …

Targeted cancer immunotherapy is designed to selectively eliminate tumor cells without
harming the surrounding healthy tissues. The death-associated protein kinases (DAPk) are …

Background Recent diagnostic procedure advances have greatly improved early lung
cancer detection. However, the invasive, unpleasant and inconvenient nature of current …

We investigated the methylation state of the epidermal growth factor receptor (EGFR) gene
promoter in non-small cell lung cancer (NSCLC) and analyzed its effect on tumor biology …