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Forty years since the structural elucidation of platelet-activating factor (PAF): historical, current, and future research perspectives
In the late 1960s, Barbaro and Zvaifler described a substance that caused antigen induced
histamine release from rabbit platelets producing antibodies in passive cutaneous …
histamine release from rabbit platelets producing antibodies in passive cutaneous …
Protective effect of olive oil microconstituents in atherosclerosis: emphasis on PAF implicated atherosclerosis theory
Atherosclerosis is a progressive vascular multifactorial process. The mechanisms
underlining the initiating event of atheromatous plaque formation are inflammation and …
underlining the initiating event of atheromatous plaque formation are inflammation and …
Micronutrients, phytochemicals and mediterranean diet: A potential protective role against COVID-19 through modulation of PAF actions and metabolism
The new coronavirus disease 2019 (COVID-19) pandemic is an emerging situation with high
rates of morbidity and mortality, in the pathophysiology of which inflammation and …
rates of morbidity and mortality, in the pathophysiology of which inflammation and …
Inflammation, bioactive lipids and atherosclerosis: potential roles of a lipoprotein-associated phospholipase A2, platelet activating factor-acetylhydrolase
AD Tselepis, MJ Chapman - Atherosclerosis Supplements, 2002 - Elsevier
It is well established that inflammation is an integral feature of atherosclerosis and of the
cardiovascular diseases which it underlies. Oxidative stress is also recognized as a key …
cardiovascular diseases which it underlies. Oxidative stress is also recognized as a key …
COVID‐19, microthromboses, inflammation, and platelet activating factor
Recent articles report elevated markers of coagulation, endothelial injury, and
microthromboses in lungs from deceased COVID‐19 patients. However, there has been no …
microthromboses in lungs from deceased COVID‐19 patients. However, there has been no …
Oxidized phospholipids and lipoprotein‐associated phospholipase A2 (Lp‐PLA2) in atherosclerotic cardiovascular disease: An update
Inflammation and oxidative stress conditions lead to a variety of oxidative modifications of
lipoprotein phospholipids implicated in the occurrence and development of atherosclerotic …
lipoprotein phospholipids implicated in the occurrence and development of atherosclerotic …
[HTML][HTML] Invited review: The anti-inflammatory properties of dairy lipids
Dairy product consumption is often associated with negative effects because of its naturally
high levels of saturated fatty acids. However, recent research has shown that dairy lipids …
high levels of saturated fatty acids. However, recent research has shown that dairy lipids …
Τhe role of lipoprotein-associated phospholipase A2 in atherosclerosis may depend on its lipoprotein carrier in plasma
CC Tellis, AD Tselepis - Biochimica et Biophysica Acta (BBA)-Molecular …, 2009 - Elsevier
Platelet-activating factor (PAF) acetylhydrolase exhibits a Ca2+-independent phospholipase
A2 activity and degrades PAF as well as oxidized phospholipids (oxPL). Such phospholipids …
A2 activity and degrades PAF as well as oxidized phospholipids (oxPL). Such phospholipids …
Platelet activating factor—a molecular link between atherosclerosis theories
The most common causes of death in westernized societies remain heart disease and
stroke. For this reason the prevention of atherosclerosis is a major objective of modern …
stroke. For this reason the prevention of atherosclerosis is a major objective of modern …
PAF-degrading acetylhydrolase is preferentially associated with dense LDL and VHDL-1 in human plasma: catalytic characteristics and relation to the monocyte …
AD Tselepis, C Dentan, SAP Karabina… - … , and vascular biology, 1995 - ahajournals.org
In human plasma, platelet activating factor (PAF)–degrading acetylhydrolase
(acetylhydrolase) is principally transported in association with LDLs and HDLs; this enzyme …
(acetylhydrolase) is principally transported in association with LDLs and HDLs; this enzyme …