Mesenchymal stem cells for spinal cord injury: current options, limitations, and future of cell therapy
Spinal cord injury (SCI) constitutes an inestimable public health issue. The most crucial
phase in the pathophysiological process of SCI concerns the well-known secondary injury …
phase in the pathophysiological process of SCI concerns the well-known secondary injury …
Mesenchymal stem cells secretome: a new paradigm for central nervous system regeneration?
The low regeneration potential of the central nervous system (CNS) represents a challenge
for the development of new therapeutic strategies. Mesenchymal stem cells (MSCs) have …
for the development of new therapeutic strategies. Mesenchymal stem cells (MSCs) have …
Phylogenetic distinction of iNOS and IDO function in mesenchymal stem cell-mediated immunosuppression in mammalian species
Mammalian mesenchymal stem cells (MSCs) have been shown to be strongly
immunosuppressive in both animal disease models and human clinical trials. We have …
immunosuppressive in both animal disease models and human clinical trials. We have …
Allogeneic and xenogeneic transplantation of adipose-derived stem cells in immunocompetent recipients without immunosuppressants
Mesenchymal stem cells (MSCs) are well known for their immunomodulatory capabilities. In
particular, their immunosuppressive property is believed to permit their allogeneic or even …
particular, their immunosuppressive property is believed to permit their allogeneic or even …
Mesenchymal stem cells improve locomotor recovery in traumatic spinal cord injury: systematic review with meta-analyses of rat models
RS Oliveri, S Bello, F Biering-Sørensen - Neurobiology of disease, 2014 - Elsevier
Traumatic spinal cord injury (SCI) is a devastating event with huge personal and societal
costs. A limited number of treatments exist to ameliorate the progressive secondary damage …
costs. A limited number of treatments exist to ameliorate the progressive secondary damage …
Coenzyme Q10 Regulation of Apoptosis and Oxidative Stress in H2O2 Induced BMSC Death by Modulating the Nrf‐2/NQO‐1 Signaling Pathway and Its Application …
X Li, J Zhan, Y Hou, Y Hou, S Chen… - Oxidative medicine …, 2019 - Wiley Online Library
Spinal cord injury (SCI) has always been considered to be a devastating problem that
results in catastrophic dysfunction, high disability rate, low mortality rate, and huge cost for …
results in catastrophic dysfunction, high disability rate, low mortality rate, and huge cost for …
Long-term results of spinal cord injury therapy using mesenchymal stem cells derived from bone marrow in humans
JH Park, DY Kim, IY Sung, GH Choi, MH Jeon… - …, 2012 - journals.lww.com
BACKGROUND: Although the transplantation of mesenchymal stem cells (MSCs) after
spinal cord injury (SCI) has shown promising results in animals, less is known about the …
spinal cord injury (SCI) has shown promising results in animals, less is known about the …
Allogeneic mesenchymal stem cells for treatment of AKI after cardiac surgery
M Swaminathan, M Stafford-Smith… - Journal of the …, 2018 - journals.lww.com
AKI after cardiac surgery remains strongly associated with mortality and lacks effective
treatment or prevention. Preclinical studies suggest that cell-based interventions may …
treatment or prevention. Preclinical studies suggest that cell-based interventions may …
The role of mesenchymal stem cells (MSCs) in veterinary medicine and their use in musculoskeletal disorders
P Prządka, K Buczak, E Frejlich, L Gąsior, K Suliga… - Biomolecules, 2021 - mdpi.com
Regenerative medicine is a dynamically develo** field of human and veterinary medicine.
The animal model was most commonly used for mesenchymal stem cells (MSCs) treatment …
The animal model was most commonly used for mesenchymal stem cells (MSCs) treatment …
Comparison of mesenchymal stromal cells from human bone marrow and adipose tissue for the treatment of spinal cord injury
Z Zhou, Y Chen, H Zhang, S Min, B Yu, B He, A ** - Cytotherapy, 2013 - Elsevier
Background aims Bone marrow and subcutaneous adipose tissue are both considered
prospective sources of mesenchymal stromal cells (MSCs), which can be used in cell …
prospective sources of mesenchymal stromal cells (MSCs), which can be used in cell …