Abstract The original Human Connectome Project yielded a rich data set on structural and
functional connectivity in a large sample of healthy young adults using improved methods of …

Hippocampal atrophy, as evidenced using magnetic resonance imaging (MRI), is one of the
most validated, easily accessible and widely used biomarkers of Alzheimer's disease (AD) …

Automated analysis of MRI data of the subregions of the hippocampus requires
computational atlases built at a higher resolution than those that are typically used in current …

The hippocampus has a pivotal role in learning and in the formation and consolidation of
memory and is critically involved in the regulation of emotion, fear, anxiety, and stress …

Importance Meta-analyses of randomized clinical trials have indicated that improved
hypertension control reduces the risk for cognitive impairment and dementia. However, it is …

Over the last two decades, numerous human MRI studies of neuroplasticity have shown
compelling evidence for extensive and rapid experience-induced brain plasticity in vivo. To …

Episodic memory critically depends on the hippocampus to bind the features of an
experience into memory. Episodic memory develops in childhood and adolescence, and …

A major focus of Alzheimer's disease (AD) research has been finding sensitive outcome
measures to disease progression in preclinical AD, as intervention studies begin to target …

Increasing evidence has shown a higher sensitivity of Alzheimer's disease (AD) progression
by local hippocampal atrophy rather than the whole volume. However, existing …

The measurement of hippocampal volumes using MRI is a useful in-vivo biomarker for
detection and monitoring of early Alzheimer's disease (AD), including during the amnestic …