Felid herpesvirus type 1 infection in cats: a natural host model for alphaherpesvirus pathogenesis

R Maes - International Scholarly Research Notices, 2012 - Wiley Online Library
Feline herpesvirus 1 (FeHV‐1) is an alphaherpesvirus that causes feline viral rhinotracheitis,
an important viral disease of cats on a worldwide basis. Acute FeHV‐1 infection is …

Intranasal brain-targeted clonazepam polymeric micelles for immediate control of status epilepticus: in vitro optimization, ex vivo determination of cytotoxicity, in vivo …

SA Nour, NS Abdelmalak, MJ Naguib, HM Rashed… - Drug …, 2016 - Taylor & Francis
Clonazepam (CZ) is an anti-epileptic drug used mainly in status epilepticus (SE). The drug
belongs to Class II according to BCS classification with very limited solubility and high …

Pollens destroy respiratory epithelial cell anchors and drive alphaherpesvirus infection

J Van Cleemput, KCK Poelaert, K Laval, F Impens… - Scientific reports, 2019 - nature.com
Pollens are well-known triggers of respiratory allergies and asthma. The pollen burden in
today's ambient air is constantly increasing due to rising climate change and air pollution …

Brain targeting efficiency of intranasal clozapine-loaded mixed micelles following radio labeling with Technetium-99m

S Sayed, FM Elsharkawy, MM Amin… - Drug Delivery, 2021 - Taylor & Francis
The research objective is to design intranasal (IN) brain targeted CLZ-loaded polymeric
nanomicellar systems (PNMS) aiming to improve central systemic CLZ bioavailability. Direct …

Replication kinetics of neurovirulent versus non-neurovirulent equine herpesvirus type 1 strains in equine nasal mucosal explants

AP Vandekerckhove, S Glorieux… - Journal of General …, 2010 - microbiologyresearch.org
Equine herpesvirus type 1 (EHV-1) is the causative agent of equine herpes
myeloencephalopathy, of which outbreaks are reported with increasing frequency …

[HTML][HTML] Aspergillus fumigatus spore proteases alter the respiratory mucosa architecture and facilitate equine herpesvirus 1 infection

J Portaels, E Van Crombrugge, W Van Den Broeck… - Viruses, 2024 - mdpi.com
Numerous Aspergillus fumigatus (Af) airborne spores are inhaled daily by humans and
animals due to their ubiquitous presence. The interaction between the spores and the …

Access to a main alphaherpesvirus receptor, located basolaterally in the respiratory epithelium, is masked by intercellular junctions

J Van Cleemput, KCK Poelaert, K Laval, R Maes… - Scientific reports, 2017 - nature.com
The respiratory epithelium of humans and animals is frequently exposed to
alphaherpesviruses, originating from either external exposure or reactivation from latency …

Immunological characterization of the equine airway epithelium and of a primary equine airway epithelial cell culture model

AM Quintana, GA Landolt, KM Annis… - Veterinary immunology …, 2011 - Elsevier
Our understanding of innate immunity within the equine respiratory tract is limited despite
growing evidence for its key role in both the immediate defense and the sha** of …

[PDF][PDF] Lactoferrin inhibits E. coli O157:H7 growth and attachment to intestinal epithelial cells.

MA Yekta, F Verdonck, W Broeck, BM Goddeeris… - 2010 - researchgate.net
Enterohemorrhagic Escherichia coli (EHEC) serotype O157: H7 strains are associated with
haemorraghic colitis and haemolytic uremic syndrome (HUS) in humans. Cattle are a …

Equine alphaherpesviruses (EHV-1 and EHV-4) differ in their efficiency to infect mononuclear cells during early steps of infection in nasal mucosal explants

AP Vandekerckhove, S Glorieux, AC Gryspeerdt… - Veterinary …, 2011 - Elsevier
Equine herpesvirus type 1 (EHV-1) replicates extensively in the epithelium of the upper
respiratory tract, after which it can spread throughout the body via a cell-associated viremia …