Dementia is a neurodegenerative condition that is considered a major factor contributing to
cognitive decline that reduces independent function. Pathophysiological pathways are not …

Pain prevalence among adults in the United States has increased 25% over the past two
decades, resulting in high health-care costs and impacts to patient quality of life. In the last …

By controlling several antioxidant and detoxifying genes at the transcriptional level,
including NAD (P) H quinone oxidoreductase 1 (NQO1), multidrug resistance-associated …

Quercetin (Qu) is a powerful flavanol antioxidant that is naturally found in plants and is part
of the flavonoid family. Qu has a wide range of biological properties, such as …

Medicinal use of Cannabis sativa L. has an extensive history and it was essential in the
discovery of phytocannabinoids, including the Cannabis major psychoactive compound—Δ9 …

Cyclophosphamide has drastically enhanced the expectancy and quality of life of cancer
patients. However, it is accompanied by diverse neurological complications which are …

Cyclophosphamide (CPA) is a chemotherapeutic drug used for various types of cancers.
However, patients receiving CPA for long periods suffer cognitive impairment associated …

The clinical usage of doxorubicin (DOX), a potent anthracycline antineoplastic drug, is often
limited by its cardiotoxic effects. Thus, for improving usage of DOX, the aim of this study was …

Rationale Chemotherapy-induced cognitive impairment (CICI), chemobrain, and chemofog
are the common terms for mental dysfunction in a cancer patient/survivor under the influence …

Bortezomib (BTZ), a proteasome inhibitor, causes dose-limiting peripheral neuropathy in
humans. Berberine (BBR), which has various biological and pharmacological properties, is …