Delivering transformative action in paediatric pain: a Lancet Child & Adolescent Health Commission
Executive summary Every infant, child, and adolescent will experience pain at times
throughout their life. Childhood pain ranges from acute to chronic, and includes procedural …
throughout their life. Childhood pain ranges from acute to chronic, and includes procedural …
Exploring the evidence for epigenetic regulation of environmental influences on child health across generations
Environmental exposures, psychosocial stressors and nutrition are all potentially important
influences that may impact health outcomes directly or via interactions with the genome or …
influences that may impact health outcomes directly or via interactions with the genome or …
Metals exposures and DNA methylation: current evidence and future directions
Abstract Purpose of the Review Exposure to essential and non-essential metals is
widespread. Metals exposure is linked to epigenetic, particularly DNA methylation …
widespread. Metals exposure is linked to epigenetic, particularly DNA methylation …
Increased paternal corticosterone exposure influences offspring behaviour and expression of urinary pheromones
Background Studies have shown that paternal stress prior to conception can influence the
innate behaviours of their offspring. The evolutionary impacts of such intergenerational …
innate behaviours of their offspring. The evolutionary impacts of such intergenerational …
Memory macrophages
M Kloc, JZ Kubiak, R Zdanowski… - International journal of …, 2022 - mdpi.com
Immunological memory is a crucial part of the immune defense that allows organisms to
respond against previously encountered pathogens or other harmful factors. Immunological …
respond against previously encountered pathogens or other harmful factors. Immunological …
The role of pharmacogenetics in personalizing the antidepressant and anxiolytic therapy
Pharmacotherapy for neuropsychiatric disorders, such as anxiety and depression, has been
characterized by significant inter-individual variability in drug response and the development …
characterized by significant inter-individual variability in drug response and the development …
A review on epigenetic inheritance of experiences in humans
If genetics defines the inheritance of DNA, epigenetics aims to regulate and make it
adaptable. Epigenetic alterations include DNA methylation, chromatin remodelling, post …
adaptable. Epigenetic alterations include DNA methylation, chromatin remodelling, post …
The effects of cadmium on the development of Drosophila and its transgenerational inheritance effects
Y Mu, X Hu, P Yang, L Sun, W Gu, M Zhang - Toxicology, 2021 - Elsevier
A new focus in toxicology research is the impact of parental exposure to environmental toxic
substances on the characteristics of offspring. In the present study, newly produced eggs of …
substances on the characteristics of offspring. In the present study, newly produced eggs of …
Contributions of epigenetic inheritance to the predisposition of major psychiatric disorders: Theoretical framework, evidence, and implications
Susceptibility to psychiatric disorders seems to be influenced by environmental disturbances
throughout all stages of life. Epigenetics is described as a key “bridge” between gene and …
throughout all stages of life. Epigenetics is described as a key “bridge” between gene and …
Epigenetic aging of mammalian gametes
The process of aging refers to physiological changes that occur to an organism as time
progresses and involves changes to DNA, proteins, metabolism, cells, and organs. Like the …
progresses and involves changes to DNA, proteins, metabolism, cells, and organs. Like the …