Regulation of filaggrin, loricrin, and involucrin by IL-4, IL-13, IL-17A, IL-22, AHR, and NRF2: pathogenic implications in atopic dermatitis
M Furue - International journal of molecular sciences, 2020 - mdpi.com
Atopic dermatitis (AD) is an eczematous, pruritic skin disorder with extensive barrier
dysfunction and elevated interleukin (IL)-4 and IL-13 signatures. The barrier dysfunction …
dysfunction and elevated interleukin (IL)-4 and IL-13 signatures. The barrier dysfunction …
[HTML][HTML] Aryl hydrocarbon receptor and intestinal immunity
B Lamas, JM Natividad, H Sokol - Mucosal immunology, 2018 - Elsevier
Aryl hydrocarbon receptor (AhR) is a member of the basic helix–loop–helix–(bHLH)
superfamily of transcription factors, which are associated with cellular responses to …
superfamily of transcription factors, which are associated with cellular responses to …
[HTML][HTML] What are the 100 most cited fungal genera?
The global diversity of fungi has been estimated between 2 to 11 million species, of which
only about 155 000 have been named. Most fungi are invisible to the unaided eye, but they …
only about 155 000 have been named. Most fungi are invisible to the unaided eye, but they …
Commensal microbiota regulates skin barrier function and repair via signaling through the aryl hydrocarbon receptor
The epidermis forms a barrier that defends the body from desiccation and entry of harmful
substances, while also sensing and integrating environmental signals. The tightly …
substances, while also sensing and integrating environmental signals. The tightly …
Aryl hydrocarbon receptor ligands in cancer: friend and foe
The aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor that is best
known for mediating the toxicity and tumour-promoting properties of the carcinogen 2, 3, 7, 8 …
known for mediating the toxicity and tumour-promoting properties of the carcinogen 2, 3, 7, 8 …
Malassezia ecology, pathophysiology, and treatment
Malassezia are lipid dependent basidiomycetous yeasts that inhabit the skin and mucosa of
humans and other warm-blooded animals, and are a major component of the skin …
humans and other warm-blooded animals, and are a major component of the skin …
Living in your skin: microbes, molecules, and mechanisms
Human skin functions as a physical, chemical, and immune barrier against the external
environment while also providing a protective niche for its resident microbiota, known as the …
environment while also providing a protective niche for its resident microbiota, known as the …
Malassezia-Associated Skin Diseases, the Use of Diagnostics and Treatment
DML Saunte, G Gaitanis, RJ Hay - Frontiers in cellular and infection …, 2020 - frontiersin.org
Yeasts of the genus, Malassezia, formerly known as Pityrosporum, are lipophilic yeasts,
which are a part of the normal skin flora (microbiome). Malassezia colonize the human skin …
which are a part of the normal skin flora (microbiome). Malassezia colonize the human skin …
The aryl hydrocarbon receptor: connecting immunity to the microenvironment
The aryl hydrocarbon receptor (AhR) is a cytoplasmic receptor and transcription factor
activated through cognate ligand binding. It is an important factor in immunity and tissue …
activated through cognate ligand binding. It is an important factor in immunity and tissue …
The role of Th17-related cytokines in atopic dermatitis
M Sugaya - International journal of molecular sciences, 2020 - mdpi.com
T helper-17 (Th17) cells, which mainly produce IL-17, are associated with development of
various autoimmune diseases such as rheumatoid arthritis, inflammatory bowel diseases …
various autoimmune diseases such as rheumatoid arthritis, inflammatory bowel diseases …