Rheumatoid arthritis (RA) is a debilitating autoimmune disease with grave physical,
emotional and socioeconomic consequences. Despite advances in targeted biologic and …

Objectives Rheumatoid arthritis is a chronic autoimmune disease manifested clinically by
polyarthralgia associated with joint dysfunction triggering the antibodies targeting against …

Osteoarthritis affects over 300 million people worldwide. Here, we conduct a genome-wide
association study meta-analysis across 826,690 individuals (177,517 with osteoarthritis) and …

Rheumatoid arthritis (RA) is a classic autoimmune disease characterized by uncontrolled
synovial proliferation, pannus formation, cartilage injury, and bone destruction. The specific …

The RANK–RANKL–OPG system is a complex signaling pathway that plays a critical role in
bone metabolism, mammary epithelial cell development, immune function, and cancer …

Joint replacement surgery is the most effective treatment for end-stage arthritis. Aseptic
loosening caused by periprosthetic osteolysis is a common complication after joint …

Background To this day, empirical data suggests that zinc has important roles in matrix
synthesis, bone turnover, and mineralization and its beneficial effects on bone could be …

Duchenne muscular dystrophy (DMD) is the most severe form of muscular dystrophy which
leads to progressive muscle degeneration and inflammation. The receptor activator of …

The biological phenomenon of cell fusion plays a crucial role in several physiological
processes, including wound healing and tissue regeneration. Here, it is assumed that bone …

Polyphenols are increasingly investigated for the treatment of periodontitis and research on
their use in dental biomaterials is currently being conducted. Grape pomace extracts are a …